Home ／About／Faculty／Professor／Dr. Hui-Fen Wu

Dr. Hui-Fen Wu
Dr. Hui-Fen Wu Professor
Research Areas Nano-biomedical analysis, Nano-microorganism analysis, Nano-proteomics, Cancer diagnosis and treatment
highest education Ph. D., University of Texas at Austin, USA
Research room SC4025
laboratory SC4030
phone (07)5252000 分機3955
E-mail hwu@faculty.nsysu.edu.tw
web https://chem2.nsysu.edu.tw/var/file/180/1180/img/780/hf_wu_e.htm
 Personal profile

學歷Education

PhD., University of Texas at Austin, USA (1994)

M.S., University of Texas at Austin, USA (1992)

B.S., National Taiwan Normal University (1989)

經歷Experience

Professor, National Sun Yat - Sen University (2006)

Professor, Tamkang University (2001)

Associate Professor, Tamkang University (1996)

Postdoctorate, University of California at Berkeley, USA (1996)

Using modified nanoparticles prepared in organic solvent as electrostatic or hydrophobic affinity probes and also combined the liquid-phase microextraction (LPME) techniques for separation and preconcentration of proteins in biological samples prior to MALDI-TOF and ESI –ion trap mass spectrometry.

Developing methods for efficient extraction and rapid enrichment of proteins in biological samples by using nanoparticles or quantum dots in MALDI- MS and ESI-MS.

Developing single drop organic nanoprobes for protein analysis in MALDI-MS and ESI-MS by synthesizing surface modification nanoparticles.

Enrichment of mass spectrometric signals by nanomaterials and quantum dots in MALDI and ESI-MS.

Developing nano materials and quantum dots for acceleration of microwave assisted enzamatic digestions of proteins and phosphoproteins.

Analysis of proteins from microorganisms by MALDI and ESI mass spectrometry.

Developing phosphopeptide enrichment techniques by using nanomaterials.

Developing nano materials and quantum dots as the matrix for protein analysis in MALDI-MS.

Probing the binding interactions of nanoparticles and quantum dots with proteins.

    著作Works
  1. Suresh Kailasa, Hui-Fen Wu*, Comprehensive Sampling and Sample Preparation. Volume 3, Chapter title: Inorganic Contaminants: Sample Preparation Approaches. Pawliszyn, J.; Le, X. C.; Li, X-F.; Lee, H. K.; Eds; Elsevier, Academic Press: Oxford, UK, 2012, 743–782. (With author’s photo and biography).
  2. Suresh Kailasa, Hui-Fen Wu*, Vaibhavkumar Mehta, Quantum Dots: Applications, Synthesis and Characterization. Chapter 5: Prospects of Engineering Quantum Dots Applications in Ultrasensitive Assays, Nova Science Publishers, 2012, 69-109.
  3. Suresh Kailasa, Hui-Fen Wu*, Cysteine: Biosynthesis, Chemical Structure and Toxicity.Chapter 3: Toxicity of Cysteine: Towards Biopathways. Editors: Fyodor V Chorkina, Andrey I. Karataev, Nova Science Publishers, 2012, 61-84.
  4. Suresh Kailasa and Hui-Fen Wu*, Lysozymes: Sources, Functions and Role in Disease. Chapter 5: Functions of Lysozymes and their identification of by MALDI-MS. Nova Science Publishers, 2013, 155-169.
  5. Suresh Kailasa, Hui-Fen Wu*, Shang-Da Huang*, Waste Water-Treatment Technologies and Recent Developments . Chapter 5: Recent developments on mass spectrometric techniques for pesticide analysis from waste water. In Tech Publications, 2013, 99-120. (This chapter has 1500 downloads on Dec 14, 2013).
  6. Suresh Kailasa, Karuna A. Rawat, Hui-Fen Wu*, Ionic Liquids in Bioanalysis, ebook entitled"Sample extraction techniques for biological samples: recent advances and novel applications”. Future Science Group, UK, London, 2014, accepted. (with author’s photo and biography).
  7. Suresh Kailasa, Stephanie L. D’souza, Hui-Fen Wu*, Analytical Applications of Nanoparticles in MALDI-MS for Bioanalysis, ebook entitled"Sample extraction techniques for biological samples: recent advances and novel applications” Future Science Group, UK, London, 2014, accepted. (with author’s photo and biography).
  8. Suresh Kailasa, Hui-Fen Wu*, Applications of Carbon Nanomaterials in Cellular Imaging for publication in the Multi-Volume SET (I-XI), Applications of NanoBioMaterials, Volume VIII: NanoBioMaterials in Medical Imaging, Wiley, 2014, accepted.
  9. Hani Abdelhamid, Hui-Fen Wu*, Book:Reference Module in Chemical, Molecular Sciences and Chemical Engineering, Chapter:11016, Ionic Liquid Matrices for Mass Spectrometry: Design, Synthesis,and Applications, Elsevier, 2014, accepted.
  10. Suresh Kailasa, Hui-Fen Wu*, Jignesh Kumar, Graphene Science Handbook: Applications and Industrialization. Vol. 6, Chapter title: Graphene-Based Laser Desorption/Ionization Mass Spectrometry: An Approach to Bioanalytical Applications, CRC Press/Taylor&Francis, FL, USA, 2014, in press.
  11. Suresh Kailasa, Hui-Fen Wu*, Chapter 34: Proteomic profiling by nanomaterials-based MALDI mass spectrometry - principles and examples. Book title: Analytical methods and integrated work-flows for Proteomic profiling, Springer, Germany, 2015, 479-496.
  12. Suresh Kailasa, Hui-Fen Wu*, Jignesh Kumar, Graphene Science Handbook: Applications and Industrialization. Vol. 6, Chapter title: Graphene-Based Laser Desorption/Ionization Mass Spectrometry: An Approach to Bioanalytical Applications, CRC Press/Taylor&Francis, FL, USA, 2016, in press.
  13. Suresh Kailasa, Vaibhavkumar N. Mehta, Nazim Hasan, Hui-Fen Wu*, Applications of Carbon Nanomaterials in Biosensing and Cellular Imaging, Elsevier, 2016, in press (proof 2/23-).
  14. Suresh Kailasa, Vaibhavkumar N. Mehta, Hui-Fen Wu*, Food Preservation: Nanotechnology in the Agri-Food Industry, Volume 6, Chapter 13: Recent Advances in the Direct and Nanomaterials –Based Matrix Assisted Laser Desorption / Ionization Mass Spectrometric Approaches for Rapid Characterization and Identification of Foodborne Pathogens, Edited by Alexandru M Grumezescu, Elsevier, 2016, 449-485.
  15. Hani Abdelhamid, Hui-Fen Wu*, Frontiers in Clinical Drug Research - Alzheimer Disorders Volum 6, Chapter 1, Biological Mass Spectrometry for Diagnosis of Alzheimer’s Disease, 2016, Vol.6, 3-22, Bentham ebooks, eBook Reference No: 9781681083391-16-1038.
  16. Hani Abdelhamid, Hui-Fen Wu*, Nanoparticles Advances drug delivery: Strategies, Pros and Cons, Nanoconjugate Nanocarriers for Drug Delivery, Apple Academic Press, worldwide distribution by CRC Press, a Taylor & Francis Group, 2017, accepted.
  17. Hui-Fen Wu, Suresh Kailasa, Nazim Hasan, Apparatus and method of liquid nitrogen assisted spray ionization mass spectrometry. 發明專利核准審定書(學校編號 101034TW),台灣發明專利 No.101129644 (101/8/16 applied-103/10/28 issued).
  18. Hui-Fen Wu, Judy Gopal, Muthu Manikandan, Nazim Hasan, Bacterio-toxicity/compatibility of Platinum nanoparticles, 2013, Jan. No.: 101081TW. 台灣發明專利.
  19. Hui-Fen Wu, Judy Gopal, Hani Abdelhamid, Pei-Yang Hua, Chitosan nanomagnets for effective extraction and sensitive mass spectrometric detection of pathogenic bacterial endotoxin from human urine, 2013, Mar. No: 102027TW. 台灣發明專利.
  20. Hui-Fen Wu, Muthu Manikandan, Nazim Hasan, PK1322, 鉑奈米粒子用於製備治療癌症藥物 的用途, 發明專利核准審定書(學校編號 102028TW), Platinum nanoparticles for treatment of cancer,台灣發明專利, No.102137386 (102/10/16 applied-104/7/20 issued).
  21. Hui-Fen Wu, Hani Abdelhamid, PK13231, 石墨烯磁性甲殼素聚合物之用途，發明專利核准審定書 ( 學校編號 102039TW), Graphene magnetic chitosan and its use. 台灣發明專利,No.102138937 (102/10/28 applied-104/6/17 issued).
  22. Hui-Fen Wu, Hani Abdelhamid, Furoic Acids as new matrices for matrix assisted laser desorption/ionization mass spectrometry, Taiwan Patent applied 2013, May. 台灣發明專利(104/9 issued).
  23. Hui-Fen Wu, Hani Abdelhamid, 甲芬那酸為新基質 之用途 Mefenamic acids as a new matrice for matrix assisted laser desorption/ionization mass spectrometry, Taiwan Patent, 2016, March issued. 台灣發明專利
    專利Patents