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王家蓁

王家蓁 副教授兼氣膠科學研究中心主任
研究領域 氣膠物理化學、氣膠生醫科學、分子光譜、化學反應動力學、 生物物理化學、藥物開發、PM2.5污染源防治及淨化、實驗設備技術研發
最高學歷 美國加州柏克萊分校博士
研究室 理3007
實驗室 理3007
電話 (07)5252000 分機3941
E-mail chiawang@mail.nsysu.edu.tw
個人網頁 http://aerosol-ccw.nsysu.edu.tw/
 個人簡介
Dr. Chia C. Wang joined the faculties of Dept. of Chemistry of NSYSU in 2010. Concerning the increasingly severe air pollution globally and particularly in Asia, Dr. Wang began her studies on Earth-related aerosols. Dr. Wang has developed the high resolution aerosol VUV photoelectron spectroscopy and applied it to study the valence electronic structures, interfacial solvation properties, surface pH of aerosols. Her research efforts include: (1) developing novel aerosol characterization techniques and instrument to advance the fundamental physicochemical properties of aerosols, (2) aerosols and their impacts to the atmospheric and marine chemistry and environmental ecosystem, (3) health effects of aerosols and biomedical implications of aerosol therapy, and (4) formation, regulation and removal of anthropogenic aerosols. Dr. Wang’s research also involves the studies of structure-function correlation of hemoglobin and hemoglobin-disorder induced hemoglobinopathies, from which she has developed new therapeutic strategies to treat Hb oxygen-transport defect and hypoxia related diseases, including chronic obstructive pulmonary diseases (COPD). Considering the tremendous impacts of air pollution and PM2.5 (particulate matters ≤ 2.5μm) to the atmosphere, air quality, environmental ecosystem and human health, Dr. Wang has taken the leading role in establishing the Aerosol Science Research Center (ASRC) of NSYSU, which was launched in May 2016 and is currently the first and only aerosol and PM2.5-themed research center in Asia. ASRC actively engages in promoting aerosol research in Taiwan and other countries in Asia, providing a platform to bring researchers from chemistry, physics, environmental engineering, public health, and biological sciences to collectively address the multi-faceted PM2.5-related issues. Dr. Wang also dedicates in the educational outreach activities to promote aerosol science and raise the awareness of environmental protection. She has curated an aerosolthemed science exhibit in 2018, held series of workshops for training seed primary and secondary school teachers for developing novel teaching materials for aerosol sciences, and in 2018, Dr. Wang established the first multi-disciplinary aerosol science program in Asia in 2018 to educate the young generations at the bachelor degree level.

學歷Education

美國加州大學柏克萊分校 博士 (Ph.D) 2007

國立台灣大學 化學研究所 碩士 (M.S.) 2001

國立高雄師範大學 化學系 學士 (B.S.) 1998

經歷Experience

2017-迄今 國立中山大學化學系副教授

2016-迄今 國立中山大學氣膠科學研究中心主任

2016-2017 國立中山大學產學營運及教育推廣處產學合作組組長

2010-2017 國立中山大學化學系助理教授

2014-2016 台灣氣膠研究學會副秘書長

2008-2010 加拿大英屬哥倫比亞大學博士後研究

2008.2-2008.8 美國勞倫斯柏克萊國家實驗室博士後研究

2001-2002 中央研究院原子與分子科學研究所研究助理

2003.1-2003.7 國立高雄女中化學科教師

1997-2001 台北市金華國中理化科教師

• 國立中山大學109學年度團隊績優教師

• 國立中山大學108學年度團隊績優教師

• 國立中山大學105學年度教學領航教師

• 國立中山大學103學年度全校優良導師

• 國立中山大學102學年度全校教學績優教師

• 國立中山大學102學年度理學院傑出教學教師代表

• 國立中山大學102學年度化學系傑出教學績優教師

• 國立中山大學100-102學年度特聘年輕學者

• 國科會100-102年度補助大專校院獎勵特殊優秀人才

氣膠物理化學、氣膠生醫科學、分子光譜、化學反應動力學、生物物理化學、藥物開發、PM2.5污染源防治及淨化、實驗設備技術研發

    著作Works
  1. Prather, K.A.*, Wang, C. C., Schooley, R. T. (2020): Reducing transmission of SARS-CoV-2, Science, 368, 1422-1424.
  2. Bagchi, A., Yu, Y., J.-H., Tsai, C.-C., Hu, W.-P., Wang, C. C.* (2020): Evidence and evolution of Criegee intermediates, hydroperoxides and secondary organic aerosols formed via ozonolysis of α-pinene, Phys. Chem. Chem. Phys., 22, 6528-6537.
  3. Chen, W.-R., Chou, C.-C., Wang, C.C.* (2019): Phthalides serve as potent modulators to boost the efficacy of fetal hemoglobin induction therapy for β-hemoglobinopathies. Blood Adv., 3, 1493-1498.
  4. Lee, F.-Y., Lee, M. S., Wallace, C. G., Huang, C.-R., Chu, C.-H., Weng, Z.-H., Huang, J.-H., Chen, X.-S., Wang, C. C.*, Yip, H.-K.* (2019): Short-interval exposure to ambient fine particulate matter (PM2.5) exacerbates the susceptibility of pulmonary damage in setting of lung ischemia-reperfusion
  5. Wang, C. C.*(2019): VUV aerosol photoelectron spectroscopy and its implications in aerosol and biomedical sciences. Chemistry, 77(2), 165-172. (invited article)
  6. Chen, W.-R., Yu, Y., Zulfajri, M., Lin, P.-C., Wu, Z.-H., Chen, M.-S., Wang, C. C.* (2017): Phthalide derivatives from Angelica sinensis decrease oxygen affinity of hemoglobin: A new allostericmodulating mechanism and potential use as 2,3-BPG substitutes. Sci. Rep. 7, 5504.
  7. Lin, P.-C., Wu, Z.-H., Chen, M.-S., Li, Y.-L., Chen, W.-R., Huang, T.-P., Lee, Y.-Y. and Wang, C. C.* (2017): Interfacial solvation and surface pH of phenol and dihydroxybenzene aqueous nanoaerosols unveiled by aerosol VUV photoelectron spectroscopy. J. Phys. Chem. B 121, 1054-1067.
  8. Chang, P.-C., Yu, Y., Wu, Z.-H., Lin, P.-C., Chen, W.-R., Su, C.-C., Chen, M.-S., Li Y.-L., Huang T.- P., Lee Y.-Y., Wang, C. C.* (2016): Molecular basis of the antioxidant capability of glutathione unraveled via aerosol VUV photoelectron spectroscopy. J. Phys. Chem. B 120, 10181-10191.
  9. Su, C.-C., Yu, Y., Chang, P.-C., Chen, Y.-W., Chen, I-Y., Lee, Y.-Y., Wang, C. C.* (2015): VUV photoelectron spectroscopy of aqueous cysteine aerosols: A microscopic view of its nucleophilicity at varying pH conditions. J. Phys. Chem. Lett. 6, 817-823.
  10. Chen, Y.-C., Hsu, C.-K., Wang, C. C., Tsai, P.-J., Wang, C.-Y., Chen, M.-R., Lin M.-Y., (2015): Particulate matter exposure in a police station located near a highway. Int. J. Environ. Res. Public Health 12, 14541-14556.
  11. Kan, H.-I., Chen, Y.-Y., Wang, C. C.* (2013): Subunit disassembly of human hemoglobin unravels the site-specific roles of its cysteine residues. J. Phys. Chem. B, 117, 9831-9839.
  12. Preston, T. C., Wang, C. C., Signorell, R. (2012): Infrared spectroscopy and modeling of cocrystalline CO2·C2H2 aerosol particles. I. The formation and decomposition of co-crystalline CO2·C2H2 aerosol particles. J. Chem. Phys. 136, 094509.
  13. Chang, K.-C., Tsai, T.-M., Chang, T.-C., Syu, Y.-E., Wang, C. C., Chuang, S.-L., Li, C.-H., Gan, D.- S., Sze, S. M. (2011): Reducing operation current of Ni-doped silicon oxide resistance random access memory by supercritical CO2 fluid treatment. Appl. Phys. Lett. 99, 263501
  14. Lang, E. K., Knox, K. J., Wang, C. C., Signorell, R. (2011): The influence of methane, acetylene and carbon dioxide on the crystallization of supercooled ethane droplets in Titan's clouds. Planet. Space Sci. 59, 722-732.
  15. Wang, C. C., Lang, E. K., Signorell, R. (2010): Methane gas stabilizes supercooled ethane droplets in Titan’s clouds. Astrophysical J. 712, L40-L43.
  16. Wang, C. C., Atreya, S. M., Signorell, R. (2010): Evidence of layered methane clouds in Titan’s atmosphere. Icarus, 206, 787-790.
  17. Kornilov, O., Wang, C. C., Healy, A. T., Leonard, M., Peng, C., Leone, S. R., Neumark, D. M., Gessner, O. (2010): Ultrafast dynamics in Helium nanodroplets probed by femtosecond time-resolved EUV photoelectron imaging. J. Phys. Chem. A 114, 1437-1445.
  18. Wang, C. C., Zielke, P., Sigurbjörnsson, Ó. F., Viteri, R., Signorell, R. (2009): Infrared Spectra of C2H6, C2H4, C2H2 and CO2 aerosols potentially formed in Titan’s Atmosphere. J. Phys. Chem. A 113, 11129-11137.
  19. Wang, C. C., Kornilov, O., Kim, J. H., Peterka, D. S., Gessner, O., Neumark, D. M. (2008): Photoelectron imaging of Helium droplets doped with Kr and Xe atoms. J. Phys. Chem. A 112, 9356-9365.
  20. Peterka, D. S., Kim, J. H., Wang, C. C., Poisson, L., Neumark, D. M. (2007): Photoionization dynamics in pure Helium droplets. J. Phys. Chem. A 111, 7449-7459.
  21. Peterka, D. S., Kim, J. H., Wang, C. C., Neumark, D. M. (2006): Photoionization and photofragmentation of SF6 in Helium nanodroplets. J. Phys. Chem. B 110, 19945-19955.
  22. Kim, J. H., Peterka, D. S., Wang, C. C., Neumark, D. M. (2006): Photoionization of Helium nanodroplets doped with rare gas atoms. J. Chem. Phys. 124, 214301.
  23. Zhang, J., Dai, D., Wang, C. C., Harich, S. A., Wang, X., Yang, X., Gustafsson, M., Skodje, R. T. (2006): State-to-state dynamics of D + H2  HD + H control of transition state pathway via reagent orientation. Phys. Rev. Lett., 96, 093201.
  24. Dai, D., Wang, C. C., Wu, G., Harich, S. A., Song, H., Hayes, M., Skodje, R. T., Wang, X., Gerlich, D. and Yang, X. (2005): State-to-state dynamics of high-n Rydberg H-atom scattering with D2. Phys. Rev. Lett. 95, 013201.
  25. Song, H., Dai, D., Wu, G., Wang, C. C., Harich, S. A., Hayes, M. Y., Wang, X., Gerlich, D., Yang, X., Skodje, R. T. (2005): Chemical reaction dynamics of Rydberg atoms with neutral molecules: a comparison of molecular-beam and classical trajectory results for the H(n) + D2 HD +D (n’). J. Chem. Phys. 123, 074314.
  26. Dai, D., Wang, C. C., Harich, S. A., Wang, X., Yang, X., Chao, S. D., Skodje, R. T. (2003): Interference of quantized transition-state pathways in the H + D2  D + HD chemical reaction. Science 300, 1730-1734.
  27. Schroden, J. J., Wang, C. C., Davis, H.F. (2003): Competition between C-C versus C-H activation in reactions of neutral Yttrium atoms with four butene isomers. J. Phys. Chem. A 107, 9295-9300.
  28. Harich, S. A., Dai, D., Wang, C. C., Yang, X., Chao, S. D., Skodje, R. T. (2002) : Forward scattering due to slow-down of the intermediate in the H + HD  D + H2 reaction. Nature 419, 281-284.
  29. Wang, C. C., Lee, Y. T., Lin, J. J., Shu, J., Lee, Y.-Y., Yang, X. (2002): Photodissociation dynamics of cyclopropane at 157 nm. J. Chem. Phys. 117, 153-160.
  30. Wang, C. C., Shu, J., Lin, J. J., Lee, Y. T., Yang, X., Nguyen, T. L., Mebel, A. M. (2002): Experimental and theoretical investigation of the O(1D) reaction with cyclopropane. J. Chem. Phys. 116, 8292-8299.
  31. Liu X., Wang, C. C., Lin, J. J., Harich, S. A. and Yang, X. (2002): Effect of a single quantum rotational excitation on state-to-state dynamics of the O(1D) + H2 reaction. Phys. Rev. Lett. 89, 133201
  32. Chao, S. D., Harich, S. A., Dai, D., Wang, C. C., Yang, X., Skodje, R. T. (2002): A full state- and angle-resolved study of the H + HD  D + H2 reaction: comparison of a molecular beam experiment to ab initio quantum reaction dynamics. J. Chem. Phys. 117, 8341-8361.
  33. Aoiz, F. J., Banares, L., Castillo, J. F., Herrero, V. J., Martinez-Haya, B., Honvault, P., Launay, J. M., Liu, X., Lin, J. J., Harich, S. A., Wang, C. C., Yang, X. (2002): The O(1D) + H2 reaction at 56 meV collision energy: a comparison between quantum mechanical, quasiclassical trajectory and crossed beam results. J. Chem. Phys. 116, 10692-10703.
  34. Shu, J., Lin, J. J., Wang, C. C., Lee, Y. T., Yang, X. (2001): Crossed beam studies of the O(1D) + NH3 reaction. J. Chem. Phys. 115, 842-848.
  35. Shu, J., Lin, J. J., Wang, C. C., Lee, Y. T., Yang, X., Nguyen, T. L., Mebel, A. M. (2001): O(1D) reaction with cyclopropane: Evidence of O atom insertion into the C-C bond. J. Chem. Phys. 115, 7-10.
  36. Lin, J. J., Wang, C. C., Lee, Y. T., Yang, X. (2000): Site-specific dissociation dynamics of ethylene at 157 nm: atomic and molecular hydrogen elimination. J. Chem. Phys. 113, 9668-9677.
    專利Patents
  1. Wang, C. C., Chen, W.-R. (2018): Method for enhancing the oxygen level of tissue cells as an alternative method for hyperbaric oxygen therapy. United States of America Patent (Patent No US 9,937,150 B2)
  2. Wang, C. C., Chen, W.-R., (2018): Method for enhancing the oxygen level of tissue cells as an alternative method for hyperbaric oxygen therapy. Republic of China Patent (Patent No TW I643615 B)
  3. Wang, C. C., Chen, W.-R. (2018): Use of phthalides in the preparation of medicinal composition for treating Alzheimer’s disease and 2,3-Biphosphoglycerate metabolism disorder induced morbidities. Republic of China Patent (Patent No TW I638655 B)
  4. Wang, C. C., Zulfajri, M., Yu, Y. (2018): A method for improving the oxygen-releasing ability of hemoglobin to organs and peripheral tissues in human bodies and a medication thereof. United States of America Patent (Patent No US 10,047,063 B2)
  5. Wang, C. C. (2017): An adjustable aerodynamic lenses system for aerodynamic focusing of aerosols. Republic of China Patent (Patent No TW I584344 B)
  6. Wang, C. C., Chen, W.-R. (2017): Method for facilitating the oxygen release of hemoglobin-based blood substitutes. United States of America Patent (Patent No US 9,713,602 B1)
  7. Wang, C. C., Zulfajri, M., Yu, Y. (2017): A method for improving the oxygen-releasing ability of hemoglobin to organs and peripheral tissues in human bodies and its medication mixture. Republic of China Patent (Patent No TW I602564 B)
  8. Wang, C. C., Zulfajri, M., Yu, Y. (2016): A use of ferulic acid for manufacturing drugs for improving the oxygen-releasing ability of hemoglobin to organs and peripheral tissues in human bodies. Republic of China Patent (Patent No TW I532482 B)