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Faculty
Contract-employed Professor
Adjunct Professor
Emeritus Chair Professor
Retired Professor
Staff

Yu-Ya Lin

  • Research Areas: Organic synthesis, bioorganic chemistry and its applications, olefin metathesis
  • Highest education: DPhil, in Chemistry, University of Oxford, UK
  • Research room: CH3020
  • Laboratory: CH4001
  • Phone：(07)5252000 ext. 3911
  • Email: yylin@mail.nsysu.edu.tw
  • Web: https://yyllab.wixsite.com/home

/ Education /

DPhil in Organic Chemistry, Chemistry Department, University of Oxford (2009-2013)
MChem (First Class Honours), Chemistry Department, University of Oxford (2004-2008)

/ Experience /

國立中山大學 化學系副教授(2025/02起)
國立中山大學 化學系助理教授 (2014/02-2025)
Professor Lin Yu-Ya has had diverse interests since childhood, and by chance, she became an international student. While receiving her education in the UK, she was inspired by her high school chemistry teacher, which led her to pursue chemistry further in university. After completing her master's and doctoral training at the University of Oxford, she chose to teach at National Sun Yat-sen University in 2014. Her Ph.D. research topic, "Development and Application of Olefin Metathesis in Protein Surface Modification," has inspired her current research interests in organic synthesis, peptide synthesis, and drug development.
Teaching Excellence Awards, College of Science, National Sun Yat-sen University (2017)
Outstanding Mentor Awards, National Sun Yat-sen University (2015)
JSPS Postdoctoral Fellowship (short-term) for Foreign Researchers (2011)
EPSRC Doctoral Training Awards (2009)
Development of Organic Synthetic Strategy, Peptide Synthesis, Synthesis of biologically-active compounds, Development and Synthesis of novel functional materials

/ Works /

1. Jiang, S.-Y.; Hsieh, W.-T.; Chen, W.-S.; Liao, J.-S.; Chiang, P.-Y.; Lin, Y. A.*, Synthesis of Thiol‐Containing Oligopeptides via Tandem Activation of γ‐Thiolactones by Silver‐DABCO Pair. Asian J. Org. Chem. 2020, 9, 1638-1649.
2. Bhushan, B.; Lin, Y. A.; Bak, M.; Phanumartwiwath, A.; Yang, N.; Bilyard, M. K.; Tanaka, T.; Hudson, K. L.; Lercher, L.; Stegmann, M.; Mohammed, S.; Davis, B. G.*, Genetic Incorporation of Olefin Cross-Metathesis Reaction Tags for Protein Modification. J. Am. Chem. Soc. 2018, 140, 14599-14603.
3. Huang, K.-J.; Huang, Y.-C.; Lin, Y. A.*, Synthesis of Histidine-Containing Oligopeptides via Histidine-Promoted Peptide Ligation. Chem. Asian J. 2018, 13, 400-403.
4. Lin, Y. A.; Davis, B. G.*, Vignette: Extending the Application of Metathesis in Chemical Biology – The Development of Site-Selective Peptide and Protein Modifications. Handbook of Metathesis (ISBN: 9783527334247). Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA. Mar, 2015: 295-309.
5. Lin, Y. A.; Boutureira, O.; Lercher, L.; Bhushan, B.; Paton, R. S.; Davis, B. G.*, Rapid Cross Metathesis for Reversible Protein Modifications via Chemical Access to Se-Allyl Selenocysteine in Proteins. J. Am. Chem. Soc. 2013, 135, 12156-12159.
6. Lin, Y. A.; Davis, B. G.*, The Allylic Chalcogen Effect in Olefin Metathesis. Beilstein J. Org. Chem. 2010, 6, 1219-1228.
7. Lin, Y. A.; Chalker, J. M.; Davis, B. G.*, Olefin Cross-Metathesis on Proteins: Investigation of Allylic Chalcogen Effects and Guiding Principles in Metathesis Partner Selection. J. Am. Chem. Soc. 2010, 132, 16805-16811.
8. Lin, Y. A.; Chalker, J. M.; Davis, B. G.*, Olefin Metathesis for Site-Selective Protein Modification. ChemBioChem 2009, 10, 959-969.
9. Chalker, J. M.; Bernardes, G. J. L.; Lin, Y. A.; Davis, B. G.*, Chemical Modification of Proteins at Cysteine: Opportunities in Chemistry and Biology. Chem. Asian J. 2009, 4, 630-640.
10. Chalker, J. M.; Lin, Y. A.; Boutureira, O.; Davis, B. G.*, Enabling olefin metathesis on proteins: chemical methods for installation of S-allyl cysteine. Chem. Commun. 2009, 3714-3716.
11. Lin, Y. A.; Chalker, J. M.; Floyd, N.; Bernardes, G. J. L.; Davis, B. G.*, Allyl Sulfides Are Privileged Substrates in Aqueous Cross-Metathesis: Application to Site-Selective Protein Modification. J. Am. Chem. Soc. 2008, 130, 9642-9643.

/ Patents /