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/ Members /

Faculty
Contract-employed Professor
Adjunct Professor
Emeritus Chair Professor
Retired Professor
Staff

Chung-Hsuan Chen

/ Education /

B.S., 1969, National Taiwan University, Taiwan
M.S., 1971, The University of Chicago, USA
Ph.D., 1974, The University of Chicago, USA

/ Experience /

Research Staff Member, Oak Ridge National Laboratory (1974–1989)
Senior Research Scientist, Oak Ridge National Laboratory (1989–2005)
Research Fellow & Key Technology Division Head, GRC, Academia Sinica (2005–)
Distinguished Research Fellow & Deputy Director, GRC, Academia Sinica (2006–)
Adjunct Professor, Department of Chemistry, National Taiwan University (2006–)
Adjunct Distinguished Research Fellow, Institute of Atomic & Molecular Sciences, Academia Sinica (2006–)
American Physical Society Fellow (1995-)
IR-100 (100 Most Important Inventions of the Year) Awards: 3
1. Rare Gas Atom Counter (1984)
2. Crystal Laser Monitor (1987)
3. Freon Ratiometer (1992)
Health and Safety Research Division Excellence in Research Award (1991)
Honorary Professor: Tsing Hua University, Beijing (1995)
Editorial Board: Rapid Communication of Mass Spectrometry (1995)
Outstanding Scholar Award (2005)
Academia Sinica Investigator Award (2006)
International Scientist of the Year (2007)
Editorial Board: Nanomedicine (2009)
Fellows of the American Association for the Advancement of Science (AAAS) (2009)
Academician, Academia Sinica (2010)
Development of novel mass spectrometry
Kinetics and dynamics of desorption and ionization of biomolecules
Microarray technology development
Bio-nanoscience and bio-nanotechnology
Laser trapping and laser tweezers for a single cell interaction
Laser spectroscopy and non-linear processes
New DNA sequencing technologies

/ Works /

“Rapid MALDI-TOF mass spectrometric method for detection of specific polymerase chain reaction products by utilizing the 5′-3′ exonuclease activity Thermus aquaticus DNA polymerase,” N.R. Isola, Z. Liu, S.L. Allman, N.I. Taranenko, Y. Kong, and C.H. Chen, Rapid Comm. Mass Spectrom. 17, 532-537 (2003).
“Detection of Trinucleotide Repeat Containing Genes by Matrix-Assisted Laser Desorption/Ionization (MALDI) Mass Spectrometry,” C.H. Chen, N.T. Potter, and N.I. Taranenko, Method Mol. Biology 217, 91-100 (2004).
“Mass Spectrometry, High Speed DNA Fragment Sizing,” C.H. Chen, In Encyclopedia of Molecular Cell Biology and Molecular Medicine, ed.; Meyers, R. A., Eds. Wiley-VCH Verlag GmbH & Co.: Weinheim, Germany, 2005; Vol. 7, pp.589-619.
“Simultaneous mass analysis of positive and negative ions using a dual-polarity time-of-flight mass spectrometer,” S.T. Tsai, C.W. Chen, L.C.L. Huang, M.C. Huang, C.H. Chen, and Y.S. Wang, Anal. Chem. 78, 7729-7734 (2006).
“Alpha1-antitrypsin precursor in gastric juice is a novel biomarker for gastric cancer and ulcer,” P.I. Hsu, C.H. Chen, C.S. Hsieh, W.C. Chang, K.H. Lai, G..H. Lo, P.N. Hsu, F.W. Tsay, Y.S. Chen, M. Hsiao, H.C. Chen, P.J. Lu, Clin Cancer Res 13(3), 876-83 (2007).
“Charge-monitoring laser-induced acoustic desorption mass spectrometry for cell and microparticle mass distribution measurement,” W.P. Peng, H.C. Lin, H.H. Lin, M. Chu, A.L. Yu, H.C. Chang, C.H. Chen, Angew Chem Int Ed Engl 46(21), 3865-9 (2007).
“Laser-Induced Acoustic Desorption Mass Spectrometry of Single Biological Cells,” W.P. Peng, Y.C.Yang, M.W. Kang, Y.K. Tzeng, Z. Nie, H.C. Chang, W. Chang, Chen, C.H., Angew. Chem. Int. 45, 1423-1426 (2006).
“Review of a Current Role of Mass Spectrometry for Proteome Research,” C.H. Chen, Anal Chim Acta 624, 16-36 (2008).
“Charge Monitoring Cell Mass Spectrometry,” W.P. Peng, H.C. Lin, M.L. Chu, H.C. Chang, H.H. Lin, Alice L. Yu,and C.H. Chen, Analytical Chemistry 80, 2524-2530 (2008).
“Observation of peptide differences between cancer and control in gastric juice,” W.C. Chang, P.I. Hsu, Y.Y. Chen, M. Hsiao, P.J. Lu and C.H. Chen, Proteomics Clin. Appl. 2, 55-62 (2008).
“Review of a Current Role of Mass Spectrometry for Proteome Research,” C.H. Chen, Anal Chim Acta 624, 16-36 (2008).

/ Patents /