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/ Members /

Wei-Lung Tseng

/ Education /

Ph. D. in Chemistry, National Taiwan University, Taiwan
B.S., in Chemistry, Fu Jen Catholic University

/ Experience /

Journal of the Chinese Chemical Society, Associated Editor(2021-present)
Chemosensors, Review Editorial Board(2019-present)
Frontiers in Analytical Chemistry, Review Editorial Board(2013-present)
Professor, Department of Chemistry, National Sun Yat-sen University (2013–present)
Review Committee Member, Department of Natural Sciences, Ministry of Science and Technology (2018–2020)
Head, Chemistry Center Analytical Group (2018/8–2020/7)
Editor-in-Chief, "Chemistry," Chinese Chemical Society (2017–2019)
Chair, Department of Chemistry, National Sun Yat-sen University (2015–2018)
Associate Professor, Department of Chemistry, National Sun Yat-sen University (2009–2012)
Assistant Professor, Department of Chemistry, National Sun Yat-sen University (2005–2008)
Head, Operations Group, Office of Research and Development, National Sun Yat-sen University (2007–2009)
Postdoctoral Researcher, Department of Chemistry, National Taiwan University (2004–2005)
Ph.D., Department of Chemistry, National Taiwan University (2002)
B.S., Department of Chemistry, Fu Jen Catholic University (1997)
Wei-Lung Tseng's research encompasses wide areas concerned with the synthesis and application of nanoparticles in biosensors, capillary electrophoresis, surface-assisted laser desorption/ionization time-of-flight mass spectrometry, catalysis, and extraction. Moreover, he designed a series of oligonucleotides to be used as molecular beacons and optical sensors based on non-watson crick base pairing. The work traverses areas of analytical chemistry, material chemistry, and more recently bio-analytical and environmental chemistry. He has demonstrated the practical applicability of these different types of sensors for detecting heavy metal ions, aminothiols, hydrogen peroxide, cyanide, enzyme activity, single nucleotide polymorphisms and anti-cancer drug coralyne. Dr. Tseng has authored and co-authored over 140 published articles in peer-reviewed scientific journals with more than 6200 citations. The h index of 44 after 11 years of scientific activity is a clear indication of his consistent publication productivity behavior. Some of the recent highlights of the research are as follows:

Research Summary (Last Five Years): Research has focused on the synthesis of nanomaterials and their applications in sensors, cell imaging, and environmental detection. The team also designed a series of oligonucleotides based on non-Watson-Crick base pairing, used as molecular beacons and optical sensors. To date, over 130 international journal papers have been published, with more than 6,000 citations (Google Scholar data), an h-index of 44, and an FWCI of 1.6. Two papers are highly cited: Analytical Chemistry, 2010, 82, 6830-6837 Analytical Chemistry, 2010, 82, 9194-9200
Outstanding Reviewers for Journal of Materials Chemistry B (2018)
Outstanding Research Awards, National Sun Yat-sen University (2016)
Excellence Awards for NSYSU-KMU Collaborative Research (2015)
Outstanding Young Scholar Awards, Shui Mu Chemistry Foundation (2015)
Outstanding Research Awards, National Sun Yat-sen University (2012)
Outstanding Young Scholar Awards, National Sun Yat-sen University (2011)
Wu Ta-You Memorial Awards, Ministry of Science and Technology (2011)
Outstanding Young Chemist Awards, Chinese Chemical Society (2009)
Outstanding Research Awards, Department of Chemistry, National Sun Yat-sen University (2009)
Outstanding Young Scholar Awards, National Sun Yat-sen University (2008)
Outstanding Research Awards, Department of Chemistry, National Sun Yat-sen University (2006)
Yen Thesis Awards, Department of Chemistry, National Taiwan University (2002)
Dean's Awards, College of Science, National Taiwan University (2002)
1. Synthesis and Application of Fluorescent 2D
2. Synthesis of Fluorescent Gold Nanoclusters
3. Nanozymes: Biomimetic enzymes at the nanoscale
4. Degradation and Removal of Environmental Pollutants
5. Immunoassay Microplates Combined with Nanoparticle Sensing
6. Development of c-di-AMP and c-di-GMP Sensors
7. Synthesis and Application of Carbon Quantum Dots

/ Works /

1. S Santhoshkumar, Shih-Wei Wei, Chien-Cheng Kuo, Manivannan Madhu, A Santhana Krishna Kumar, Wei-Bin Tseng, Chi-Yu Lu, Wei-Lung Tseng* Engineering of phase composition in molybdenum disulfide nanoflowers to amplify SERS activity: Sensitivity enhancement through dispersive liquid-liquid microextraction integration. Sensors and Actuators B: Chemical 2025, 422, 136577.
2. Wei-Bin Tseng, Chia-Hui Hsu, Manivannan Madhu, Chi-Yu Lu, Wei-Lung Tseng* “Biotin-Modified PEGylated Protein-Stabilized Gold Nanoclusters: A strategy for selective and efficient intracellular transport of glucose oxidase for glucose detection”. Chemical Engineering Journal, 2024, 498, 155133.
3. Madhu, M., Tseng, W.B., Chou, Y.S., Krishna Kumar, A.S., Lu, C.Y., Chang, P.L. and Tseng, W.L.* “Peptide-Directed Synthesis of Aggregation-Induced Emission Enhancement-Active Gold Nanoclusters for Single-and Two-Photon Imaging of Lysosome and Expressed αvβ3 Integrin Receptors”. Anal. Chem., 2024, 96, 9007–9015.
4. S.Santhoshkumar., M.Madhu., Tseng, W.B* and Tseng, W.L * “ Gold Nanoclusters-based fluorescent sensors for in vitro and in vivo ratiometric imaging of biomolecules” Phys. Chem. Chem. Phys., 2023,25, 21787-21801.
5. S.Santhoshkumar., W.-S. Wei., M.Madhu., Tseng, W.B and Tseng, W.L * “Chemically Engineered Sulfur Vacancies on Few-Layered Molybdenum Disulfide Nanosheets for Remarkable Surface-Enhanced Raman Scattering Activity” The Journal of Physical Chemistry C, 2023, 127(18), 8803-8813.
6. A.S.Krishna Kumar, W.-B. Tseng, E. Arputharaj, P.-J. Huang, Tseng, W.L,* Tomasz Bajda* “Covalent Organic Framework Nanosheets as an Enhancer for Light-Responsive Oxidase-like Nanozymes: Multifunctional Applications in Colorimetric Sensing, Antibiotic Degradation, and Antibacterial Agents” ACS Sustain. Chem. Eng., 2023, 11(18) 6956-6969.
7. A.S. Krishna Kumar, J. Warchol, J. Matusik, Tseng. W. L,* N. Rajesh,* and T. Bajda* “Heavy metal and organic dye removal via a hybrid porous hexagonal boron nitride-based magnetic aerogel” NPJ Clean Water 2022, 5, 1-12
8. W.-B. Tseng,* J.-Y. Rau, H.-C. Chiou, Tseng. W. L * “Synthesis of gold nanoclusters-loaded lysozyme nanoparticles for ratiometric fluorescent detection of cyanide in tap water, cyanogenic glycoside-containing plants, and soils”. Environ. Res. 2021, 112144.
9. C.-H Chuang, W.-Y Chen, W.-B Tseng, A. Lin, C-Y, Lu, and Tseng. W. L * “Microwave-Mediated Synthesis of Near-Infrared-Emitting Silver Ion-Modified Gold Nanoclusters for Ratiometric Sensing of Hydrosulfide in Environmental Water and Hydrogen Sulfide in Live Cells” ACS Sustain. Chem. Eng. 2022, 10, 7, 2461–2472.
10. W.-B Tseng, Y.-S. Chou, C.-Z. Lu, M. Madhu, C.-Y. Lu and Tseng. W. L * “Fluorescence sensing of heparin and heparin-like glycosaminoglycans by stabilizing intramolecular charge transfer state of dansyl acid-labeled AG73 peptides with glutathione-capped gold nanoclusters” Biosens. Bioelectron., 2021, 193, 113522
11. A.S.K. Kumar, C.-Y. Lu and Tseng. W. L * “Two in One: Poly (ethyleneimine)-Modified MnO2 Nanosheets for Ultrasensitive Detection and Catalytic Reduction of 2, 4, 6-Trinitrotoluene and Other Nitro Aromatics”. ACS Sustain. Chem. Eng. 2021, 9, 1142-1151.
12. S.-W. Zhan, W.-B. Tseng and Tseng. W. L * “Impact of nanoceria shape on degradation of diethyl paraoxon: Synthesis, catalytic mechanism, and water remediation application”. Environ. Res. 2020, 188, 109653.
13. W.-B. Tseng, Y.-T. Lu, S.-W. Zhan and Tseng. W. L * “Self-assembly of c-di-GMP, Tb3+, and Ag+ into high-quantum-yield coordination polymer nanoparticles: Mechanism discussion and application as a c-di-GMP sensor”. Sensors and Actuator B: Chemical 2020, 312, 127960
14. M. Madhu, T.-H. Chen and Tseng. W. L * “White-light emission of single carbon dots prepared by hydrothermal carbonization of poly(diallyldimethylammonium chloride): Applications to fabrication of white-light-emitting films” J. Colloid Interf. Sci. 2019, 556, 120-127.
15. A. S. K. Kumar, J.-G. You, W.-B. Tseng, G. D. Dwivedi, N Rajesh,* S.-J. Jiang* and Tseng. W. L * “Magnetically Separable Nano-spherical g-C3N4@ Fe3O4 as a Recyclable Material for Chromium Adsorption and Visible-Light-Driven Catalytic Reduction of Aromatic Nitro Compounds” ACS Sustain. Chem. Eng. 2019, 7, 6662-6671

/ Patents /