/ Members /

Po-Ling Chang

/ Education /

2003 -2007 Ph.D, Department of Chemistry (Analytical), National Taiwan University
2000 -2002 Master, Department of Chemistry (Analytical), National Taiwan University

/ Experience /

2020- Present: Professor, National Sun Yat-sen University
2018 - 2020 Chairman of Department of Chemistry, Tunghai University
2018 - 2020 Professor of Department of Chemistry, Tunghai University
2015 - 2016 Visiting professor (Institute of Bioengineering, EPFL, Switzerland)
2013 - 2015 Director of Precision Instrument Center
2013 - 2018 Associate professor (Department of Chemistry, Tunghai University)
2009 - 2013 Assistant professor (Department of Chemistry, Tunghai University)
2007 - 2009 Postdoctoral researcher (Molecular Medicine Research Center, Chang Gung University)
1999 - 2003 Medical technologist (Department of Laboratory Medicine, Mackay Memorial Hospital)
1998 Department of Medical Laboratory Science, Yuanpei Institute of Medical Technology
New Faculty Awards, National Sun Yat-sen University (2020)
Ministry of Science and Technology Outstanding Talent Grant (2013–2019)
Outstanding Mentor Awards, Tunghai University (2012)
Outstanding Academic Publication Awards, Tunghai University (2012, 2014)
1. Development of novel biological imaging detection methods using super-resolution fluorescence microscopy
2. Molecular electrophoresis behavior in nano-capillaries, biomolecule concentration, and single-molecule sensing techniques
3. Self-assembled high-resolution scanning probe microscopy

/ Works /

1 Chang, P.-L.*; Graf, M.; Hung, C.-H.; Radenovic, A., Orthogonal tip-to-tip nanocapillary alignment allows for easy detection of fluorescent emitters in femtomolar concentrations. Nano Lett. 2018, 18 (5), 3165-3171.
2 Lin, Y.-Z.; Ou, D.-L.; Chang, H.-Y.; Lin, W.-Y.; Hsu, C.; Chang, P.-L.*, Simultaneous visualization of the subfemtomolar expression of microRNA and microRNA target gene using HILO microscopy. Chem. Sci. 2017, 8 (9), 6670-6678.
3 Chang, P.-L.; Hsieh, M.-M.; Chiu, T.-C., Recent Advances in the Determination of Pesticides in Environmental Samples by Capillary Electrophoresis. Int. J. Env. Res. Public Health 2016, 13 (4), 409.
4 Chung, Y.-A.; Chen, Y.-H.; Chang, P.-L.*, Strategies of fluorescence staining for trace total ribonucleic acid analysis by capillary electrophoresis with argon ion laser-induced fluorescence. Electrophoresis 2015, 36 (15), 1781-1784.
5 Chen, Y.-C.; Chang, P.-L.*, Baseline separation of amino acid biomarkers of hepatocellular carcinoma by polyvinylpyrrolidone-filled capillary electrophoresis with light-emitting diode-induced fluorescence in the presence of mixed micelles. Analyst 2015, 140 (3), 847-853.
6 Yu, M.-H.; Huang, Y.-C.; Chang, P.-L.*, Rapid screening of the heterogeneity of DNA methylation by single-strand conformation polymorphism and CE-LIF in the presence of electro-osmotic flow. Electrophoresis 2014, 35, 2378-2385.
7 Shih, Y.-C.; Liao, C.-R.; Chung, I.-C.; Chang, Y.-S.; Chang, P.-L.*, Simultaneous separation of five major ribonucleic acids by capillary electrophoresis with laser-induced fluorescence in the presence of electroosmotic flow: Application to the rapid screening of 5S rRNA from ovarian cancer cells. Anal. Chim. Acta 2014, 847, 73-79.
8 Lin, Y.-Z.; Chang, P.-L.*, Colorimetric Determination of DNA Methylation Based on the Strength of the Hydrophobic Interactions between DNA and Gold Nanoparticles. ACS Appl. Mater. Interfaces 2013, 5 (22), 12045-51.

/ Patents /