曾韋龍教授

◆研究室:C3007

◆實驗室:C3007

◆電話:(07)5252000 轉 3925

◆e-mail:tsengwl@mail.nsysu.edu.tw


學經歷

◇國立中山大學 教授(2012)
◇國立中山大學副教授(2009)
◇國立中山大學助理教授(2005)
◇國立台灣大學博士後研究(2003~2005)
◇國立台灣大學博士(2002)
◇國立台灣大學碩士(1998)
◇私立輔仁大學化學學士(1997)


研究興趣

1. 毛細管電泳。

2. 萃取複雜基質中之生物分子。

3. 奈米材料之合成與應用。

4. 生物分子與重金屬離子感測器



研究計畫
  1. National science council, research grant, "Development of rapid and sensitive methods for screening cancer markers (開發適合快速檢測腫瘤標記之高感度分析技術)", principal investigator, 2005/08/01-2007/07/31, award number 94-2119-M-110-016- and 95-2119-M-110-016-.

  2. National science council, research grant, "Development and application of new nanomaterials for capillary electrophoresis and surface assisted laser desorption/ionization mass spectrometry (新型奈米材料於毛細管電泳與表面輔助雷射脫附離子化質譜儀之開發與應用)", principal investigator, 2007/08/01-2010/07/31, award number 96-2113-M-110-008-, 97-2113-M-110-008-, and 98-2113-M-110-008-.

  3. National science council, research grant, "Functionalized-nanoparticle for selective extraction and enrichment of biomolecules in biological fluid prior to capillary electrophoresis (功能性奈米粒子選擇性萃取與濃縮體液內生物分子並結合毛細管電泳分離)", principal investigator, 2009/08/01-2012/07/31, award number 98-2113-M-110-009-MY3.


獎勵與榮譽

                104                          第十六屆 中山-高醫合作研究優秀獎

   104                          第十六屆 水木化學文教基金會傑出青年學者獎

   102/08-103/07          國立中山大學特聘研究學者

   101                          國立中山大學研究績優獎

   100                          國立中山大學研究績優獎(年輕學者獎)

   100/08-103/07          國立中山大學特聘年輕學者

   100                          科技部吳大猷紀念獎

   98                            中國化學會傑出青年化學獎

   97                            國立中山大學研究績優獎(年輕學者獎)

   98                            國立 中山大學化學系研究績優獎

   95                            國立中山大學化學系研究績優獎

   91                            第十一屆台灣大學化學系顏氏論文獎

   91                            九十學年度台灣大學理學院研究所院長獎


國內外邀請演講

第八屆海峽兩岸分析化學會議(2014)

Kaohsiung, Taiwan, Nov 15-18, 2015, 15th Asia-Pacific International Symposium on Microscale Separations and Analysis, invited speaker

Barcelona, Spain, July 15-17, 2015, 6th International Conference on Nanotechnology: Fundamentals and Applications, invited speaker

花蓮,台東大學,一百零三年中國化學會年會

重慶,第八屆海峽兩岸分析化學會議(2012)

一百零一年中國化學會年會

第二屆新興汙染物論壇(2012)

第七屆海峽兩岸分析化學會議 (2012年)

◇2011年中國化學會年會

◇第一屆新興汙染物論壇 (2011年)
◇第六屆海峽兩岸分析化學會議(2010年)
◇第八屆台灣質譜學會年會暨學術研討會 (2010年)
◇第五屆 海峽兩岸分析研討會暨第14屆分析技術研討會 (2008年)
◇九十七年中國化學會年會
◇九十八年中國化學會年會
◇各大學邀請演講 (2008-2010年,共10次)
◇第八屆亞太微尺標分離暨分析國際研討會(2008)
◇中山大學理學院與日本京都大學國際研討會(2009)


擔任國際重要學術學會理監事或國際知名學術期刊編輯委員

  1. 中國化學會「化學」編輯委員會,任期102年1月1日至102年12月31

  2. 2012  擔任國際期刊Dataset Papers in Nanotechnology的Editorial Board


代表著作

2016
(116) Lin, J.-H., Tseng, W.-B., Lin, K.-C., Lee, C.-Y., Chandirasekar S., Tseng, W.-L.* and Hsieh, M-M.* “Oligonucleotide-Based Fluorescent Probe for Sensing of Cyclic Diadenylate Monophosphate in Bacteria and Diadenosine Polyphosphates in Human Tear”. ACS Sensors, 2016, 1, 1132-1139.

(115) Wu, Y.-T., Shanmugam, C. Tseng, W.-B., Hiseh, M.-M. and Tseng, W.-L.* “Gold Nanocluster-Based Fluorescent Probe for Simultaneous pH and Temperature Sensing and its Application to Cellular Imaging and Logic Gates”. Nanoscale 2016, 8, 11210-11216.

(114) Yang, Y.-C. and Tseng, W.-L.* “1,4-Benzenediboronic-Acid-Induced Aggregation of Gold Nanoparticles: Application to Hydrogen Peroxide Detection and Biotin-Avidin-Mediated Immunoassay with Naked-Eye Detection”. Anal. Chem. 2016, 88, 5355

(113) Kumar, A. S. K., Jiang, S.-J.* and Tseng, W.-L.* “Facile synthesis and characterization of thiol-functionalized graphene oxide as effective adsorbent for Hg(II)”. Journal of Environmental Chemical Engineering,2016, 4, 2052-2065

(112) Ke, C.-C., Yang, Y.-C. and Tseng, W.-L.* “Synthesis of blue-, green-, yellow-, and red-emitting graphene-quantum-dot-based nanomaterials with excitation-independent emission”. Part. Part. Syst. Char. 2016, 33, 132-139. (Selected as cover)

(111) Wu, C.-Y., Hsieh, T.-J., Tseng, W.-L., Keng, C.-L. and Lu, C.-Y.* “Valproic acid analysis by mass spectrometry part I:enhanced determination of valproic acid by microwave assisted chemical labeling.” RSC Adv. 2016, 6, 1925-1929

(110) Lin, J.-H., Yang, Y.-C. Shih, Y. C. Hung, S.-Y. Lu, C.-Y. and Tseng, W.-L.* “Photoinduced electron transfer between Fe (III) and adenosine triphosphate-BODIPY conjugates: Application to alkaline-phosphatase-linked immunoassay” Biosens. & Bioelectron. 2016, 77, 242-248.

2015
(109) Kumar, A. S. K., Jiang, S.-J.* and Tseng, W.-L.* “Effective adsorption of chromium (vi)/Cr (iii) from aqueous solution using ionic liquid functionalized multiwalled carbon nanotubes as a super sorbent”. J. Mater. A 2015, 3, 7044-7057

(108) Ke, C.-Y., Wu, Y.-T. and Tseng, W.-L.* “Fluorescein-5-isothiocyanate-conjugated protein-directed synthesis of gold nanoclusters for fluorescent ratiometric sensing of an enzyme–substrate system”. Biosens. & Bioelectron. 2015, 69, 46-53

(107) Chen, T.-H., Nieh, C.-C., Ya-Chen Shih, Y.-C., Ke, C.-Y. and Tseng, W.-L.* “Hydroxyl Radical-Induced Etching of Gold Nanoparticles to Oligomeric AuI-Thiolate Complexes”. RSC Adv. 2015, 5, 45158-45164.

(106) Lee, C.-Y. and Tseng, W.-L.* “Adenosine-Based Molecular Beacons for Fluorescent Detection of Oversulfated Chondroitin Sulfate Contaminants in Heparin without Enzyme Treatment.” Anal. Chem. 2015, 87, 5031-5035

(105) Lin, J.-H., Yu, C.-J., Yang, Y.-C. and Tseng, W.-L.* “Formation of Polydopamine Dots from Hydroxyl-Radical-Induced Degradation of Polydopamine Nanoparticles. Synthesis Mechanism and Application for Sensing Ferric Ions and H2O2”. Phys. Chem. Chem. Phys. 2015, 17, 15124-15130; selected as the inside of the cover)

(104) Su, H.-H., Chuang, L.-Y., Tseng, W.-L. and Lu, C.-Y.* “Micro-scale strategy to detect spermine and spermidine by MALDI–TOF MS in foods and identification of apoptosis-related proteins by nano-flow UPLC–MS/MS after treatment with spermine and spermidine”. J. Chromatogr. B 2015, 978-979, 131-137.

(103) Hung, S.-Y. and Tseng, W.-L.* “Tween 20-Stabilized Gold Nanoparticles Combined with Adenosine Triphosphate-BODIPY Conjugates for Fluorescence Detection of Adenosine with More Than 1000-Fold Selectivity.” Anal. Chim. Acta 2015, 857, 64-70 (This article has been downloaded or viewed 387 times since publication.

(102) Lin, J.-H. and Tseng, W.-L.* “Ultrasensitive detection of target analyte-induced aggregation and growth of gold nanoparticles using laser-induced nanoparticle Rayleigh scattering”. Talanta, 2015, 132, 44-51. (This article has been downloaded or viewed 483 times since publication.

2014
(101) Shih, Y.-C., Ke, C.-Y. and Cheng-Ju Yu, C.-J. and Tseng, W.-L. “Combined Tween 20-Stabilized Gold Nanoparticles and Graphite Oxide-Fe3O4 Nanoparticle Composites for Rapid and Efficient Removal of Mercury Species in Environmental Water” ACS Materials & Interface 2014, 6, 17437-17445.

(100) Lin, K.-C. Kuo, C.-Y. Nieh, C.-C. and Tseng, W.-L.* “Use of thymine-based molecular beacon for the construction of a NAND logic gate for Triplex DNA binders. RSC Adv., 2014, 4, 38389-38392

(99) Nieh, C.-C nd Tseng, W.-L.* “Thymine-based molecular beacon for sensing adenosine based on the inhibition of S-adenosylhomocysteine hydrolase activity” Biosens. & Bioelectron. 2014, 61, 404-409. (This article has been downloaded or viewed 379 times since publication)

(98) Ke, C.-Y., Chen, T.-H., Lu, L-C. and Tseng, W.-L.* “ Thiol-induced etching of luminescent gold nanoclusters: controlling lysozyme activity and sensing thimerosal” (RSC Advance, accepted)

(97) Yu, C.-J., Jiang J.-Y. and Tseng, W.-L.* “Lysozyme-Directed Synthesis of Platinum Nanoclusters as a Mimic Oxidase for Sensing Glutathione” (Nanoscale, accepted) (the inside of back cover)

(96) Huang, S.-Y. and Tseng, W.-L.* “A polyadenosine-coralyne complex as a novel fluorescent probe for the sensitive and selective detection of heparin in plasma.” Biosens. & Bioelectron. 2014, 57, 186-191.

(95) Lin, J.-H. and Tseng, W.-L.* “Design of two and three input molecular logic gates using non-Watson-Crick base pairing-based molecular beacons” Analyst 2014, 139, 1436-1441.

(94) Chen, T.-H. and Tseng, W.-L.* “Sinapinic acid-directed syntheis of gold nanocluster and its applicatin to quantitative matrix-assisted laser desorption/ionization mass spectrometry” Nanoscale, 2014, 6, 1347-1353 (the inside of back cover)

Non-corresponding author
(93) Lu, C.-Y., Su, H.-H., Chen, Y. –L.* and Tseng, W.-L. “Micro extraction to quantitate spermidine and spermine in human urine and blood by matrix-assisted laser desorption ionization time-of-flight mass spectrometry” J. Chromatogr. A, 2014, 1326, 1- 6.

2014   Corresponding author

(94) Yu, C.-J., Jiang J.-Y. and Tseng, W.-L.* “Lysozyme-Directed Synthesis of Platinum Nanoclusters as a Mimic Oxidase for Sensing Glutathione” (reSubmitted to Nanoscale)

(93) Chen, T.-H. and Tseng, W.-L.* “Sinapinic acid-directed syntheis of gold nanocluster and its application to quantitative matrix-assisted laser desorption/ionization mass spectrometry” (Nanoscale, DOI: 10.1039/C3NR04991D) (Selected as back cover)

2013   Corresponding author

(92) Chen, T.-H. Lu, C.-Y. and Tseng, W. L.* “One-pot synthesis of two-sized metal clusters for ratiometric sensing of Hg2+” Talanta 2013, 117, 258-262

(91) Yu, C.-J., Wu, S.-M. and Tseng, W.-L.* “Magnetite Nanoparticle-Induced Fluorescence Quenching of Adenosine Triphosphate-BODIPY Conjugates: Application to Adenosine Triphosphate and Pyrophosphate Sensing” Anal. Chem. 2013, 85, 8559-8565.

(90) Kuo, C. Y. and Tseng, W.-L.* “Adenosine-based molecular beacons as light-up probes for sensing heparin in plasma” Chem. Commun. 2013, 49, 4607-4609. (Selected as inside back cover)

(89) Lin, T.-H., Lu, C.-Y. and Tseng, W.-L.* “Selective enrichment of catecholamines using iron oxide nanoparticles followed by capillary electrophoresis” Electrophoresis 2013 34 297-303

(88) Lin, J.-H. and Tseng, W.-L.* “A method for fluorescence sensing of adenosine and alkaline phosphatase based on the inhibition of S-adenosylhomocysteine hydrolase activity” Biosens & Bioelectrons. 2013, 41 379-385

2013   Non-corresponding author

(87) Chen, R.-C., Chuang, L. Y., Tseng, W.-L., Tyan, Y.-C. and Lu, C.-Y. “Determination of phosphoserine/threonine by nanoUPLC-MS/MS coupled with micro-scale labeling” Anal. Biochem. 2013, 433, 187-196.

2012   Corresponding author

(88) Lin, J.-H. and Tseng, W.-L.* “A method for fluorescence sensing of adenosine and alkaline phosphatase based on the inhibition of S-adenosylhomocysteine hydrolase activity” Biosens & Bioelectrons. 2012 (Revised)

(89) Lin, T.-H. and Tseng, W.-L.* “Selective enrichment of catecholamines using iron oxide nanoparticles followed by capillary electrophoresis” Electrophoresis 2012 (Revised)

(86) Lin, J.-H. and Tseng, W.-L.* “Gold nanoparticles for specific extraction and enrichment of bio-molecules and environmental pollutants” Review in Analytical Chemistry 2012, 31, 153-162 (invited review)

(85) Liu, C.-H., Yu, C.-J. and Tseng, W.-L.*“Fluorescence assay of catecholamines based on the inhibition of peroxidase-like activity of Fe3O4 nanoparticles” Anal. Chim Acta 2012 (Revised)

(84) Yeh, P.-R. and Tseng, W.-L.* “Human serum albumin-coated gold nanoparticles for selective extraction of lysozyme from real-world samples prior to capillary electrophoresis”J. Chromatogr. A 2012 (Revised)

(83) Liu, C.-Y. and Tseng, W.-L.* “Using polysorbate 40-stabilized gold nanoparticles in colorimetric assay of cyanogenic glycoside in plants” Anal. Methods 2012, 4, 2537

(82) Lin, Y.-H. and Tseng, W.-L.* “A room-temperature adenosine-based molecular beacon for highly sensitive detection of nucleic acids” Chem. Comm. 2012, 48, 6262-6264.

(81) Chen, T.-H. and Tseng, W.-L.* “Lysozyme type VI-stabilized Au8 clusters: synthesis mechanism and application for sensing of glutathione in a single drop of blood” Small, 2012, 8, 1912-1919.

(80) Wu, Z.-H., Lin, J.-H. and Tseng, W.-L.* “Oligonucleotide-Functionalized Silver Nanoparticle Extraction and Laser-Induced Fluorescence for Ultrasensitive Detection of Mercury(II) ion” Biosens. Bioelectron. 2012, 34, 185-190

(79) Lai, Y.-J. and Tseng, W.-L.* “Gold nanoparticle extraction followed by o-phthaldialdehyde derivatization for fluorescence sensing of different forms of homocysteine in plasma” Talanta 2012, 91, 103-109.

(78) Chen, C.-C., Tseng, W.-L.* and Hsieh, M.-M.* “Selective extraction of thiol-containing peptides in seawater using Tween 20-capped gold nanoparticles followed by capillary electrophoresis with laser-induced fluorescence”. J. Chromatogr. A 2012, 1220, 162-168.

2012   Non-corresponding author

(77) Lee, H.-C., Chen, T.-H., Tseng, W.-L. and Lin, C.-H.* “Novel core etching technique of gold nanoparticles for colorimetric dopamine detection” Analyst 2012, 137, 5352-5357

(76)Chuang, C.H., Chuang, K. H., Wang, H. E., Roffler, S. R., Tzou, S. C., Cheng, T. C., Kao, C. H., Wu, S. Y., Tseng, W.-L., Shiea, J., Wang, J. M. and Cheng, T. L.* In Vivo Positron Emission Tomography Imaging of Protease Activity by Generation of a Hydrophobic Product from a Noninhibitory Protease Substrate. Clin. Cancer Res. 2012, 18, 238-247.

(75) Chou, C.-H., Chuang, L.-Y., Tseng, W.-L. and Lu, C.-Y. “Characterization of protein adducts formed by toxic alkaloids by nano-scale liquid chromatography with mass spectrometry” J. Mass Spectrom. 2012, 47, 1303-1312

2011   Corresponding author

(74) Wu, Z.-H. andTseng, W.-L.* “Combined cloud point extraction and Tween 20-stabilized gold nanoparticles for colorimetric assay of silver nanoparticles in environmental water” Anal. Methods, 2011, 3, 2915-2920.

(73) Lin, Y.-H. andTseng, W.-L.* "Fluorescence detection of coralyne and polyadenylation reaction using an oligonucleotide-based fluorogenic probe" Chem. Commun. 2011, 47, 11134-11136.

(72) Liu, C.H. and Tseng, W.-L.* "Oxidase-functionalized Fe3O4 nanoparticles for fluorescence sensing of specific substrate" Anal. Chim. Acta 2011, 703, 87-93

(71) Lai, Y.-J. and Tseng, W.-L.* “Role of 5-thio-(2-nitrobenzoic acid)-capped goldnanoparticles in the sensing of chromium(VI): remover and sensor” Analyst 2011, 136, 2712-2717 (Back cover)

(70) Liu, F-C., Shen, C.-C. and Tseng, W.-L.* “The composites of cationic polyelectrolyte and glutathione-capped quantum dots for selective fluorescence detection of Cu2+” J. Chin. Chem. Soc. 2011, 58, 707-713

(69) Liu, C.-Y. and Tseng, W.-L.* “Colorimetric assay of cyanide and cyanogenic glycoside using polysorbate 40-stabilized gold nanoparticles” Chem. Commun. 2011, 47, 2550-2552

2010   Corresponding author

(68) Lin, J.-H., Wu, Z.-H. and Tseng, W.-L.*“Extraction of environmental pollutants using magnetic nanomaterial” Anal. Methods, 2010, 2, 1874–1879 (invited review, front cover)

(67) Chang, C.-W., Chu, S.-P. and Tseng, W.-L.* “11-mercaptoundecanoic acid-capped gold nanoparticles for the preconcentration of melamine in milk powder prior to capillary electrophoresis“ J. Chromatogr. A 2010, 1217, 7800-7806

(66) Lin, Y.-H. and Tseng, W.-L.* “Ultrasensitive Sensing of Hg2+ and CH3Hg+ “Based on the Fluorescence Quenching of Lysozyme Type VI-Stabilized Gold Nanoclusters” Anal. Chem. 2010, 82, 9194-9200.

(65) Lin, J.-H., Chang, C.-W., Wu, Z.-H. and Tseng, W.-L.* “Colorimetric Assay for S-Adenosylhomocysteine Hydrolase Activity and Inhibition Using Fluorosurfactant-Capped Gold Nanoparticles” Anal. Chem. 2010, 82, 8775-8779.

(64) Lin, C.-J., Liu, C.-H. andTseng, W.-L.* ”Fluorescein isothiocyanate-capped gold nanoparticles for fluorescent detection of reactive oxygen species based on thiol oxidation and their application for sensing glucose in serum” Anal. Methods 2010, 2, 1810-1815.

(63) Yu, C.-J, Lin, C.-Y., Liu, C.-H., Cheng, T.-L. andTseng, W.-L.* ”Synthesis of poly(diallyldimethylammonium chloride)-coated Fe3O4 nanoparticles for colorimetric sensing of glucose and selective extraction of thiol” Biosens. Bioelectron. 2010, 82, 913-917.

(62) Lin, C.-Y., Yu, C.-J., Lin, Y.-H. andTseng, W.-L.* ”Colorimetric Sensing of Silver(I) and Mercury(II) Ions Based on an Assembly of Tween 20-Stabilized Gold Nanoparticles” Anal. Chem. 2010, 82, 6830-6837. (Highly cited paper)

(61) Chang, C.-W., and Tseng, W.-L.* “Gold Nanoparticles Extraction Followed by Capillary Electrophoresis to Determine the Total, Free, Protein Bound Aminothiols in Plasma” Anal. Chem. 2010, 82, 2696-2702.

(60) Lin, J.-L., Chang, C.-W. and Tseng, W.-L.* “Fluorescent sensing of homocysteine in Urine: Using fluorosurfactant-capped gold nanoparticles and o-phthaldialdehyde” Analyst 2010, 135, 104-110 (inside cover)

(59) Huang, K.-W., Yu, C.-J. andTseng, W.-L.* “Sensitivity Enhancement in the Colorimetric Detection of Lead(II) Ion Using Gallic Acid-Capped Gold Nanoparticles: Improving Size Distribution and Minimizing Interparticle Repulsion” Biosens. Bioelectron. 2010, 25, 984-989.

2010   Non-corresponding author

(58) Yang, Y. H., Li, R. N., Tzou, S. C., Wang, J. Y., Lee, H. P., Wang, H. C., Chen, F. M., Wang, Y. H., Hsieh, M. C., Huang, M. Y., Tseng, W. L., Lin, S. R., Cheng, T. L. “Simultaneous Detection of Multiple Single-Nucleotide Polymorphisms by a Simple Membrane Chip” Genet. Test Mol. Biomarkers. 2010, 14, 653-659.

(57) W. C. Hung, W. L. Tseng, J. Shiea, H. C. Chang,* “Skp2 overexpression increases the expression of MMP-2 and MMP-9 and invasion of lung cancer cells.” Cancer Letters, 288, 156-161.

(56) K. H. Chuang, S. C. Tzou, T. C. Cheng, C. H. Kao, W. L. Tseng, J. Shiea, K. W. Liao, Y. M. Wang, Y. C. Chang, B. J. Huang, C. J. Wu, P. Y. Chu, S. R. Roffler,* and T. L. Cheng* “Measurement of Poly(ethylene glycol) by Cell-Based Anti-poly(ethylene glycol) ELISA” Anal. Chem. 2010 82, 2355–2362.

(55) Chuang, K.H., Wang, H. E., Cheng, T. C., Tzou, S. C., Tseng, W. L., Hung, W. C., Tai, M. H., Chang, T. K., Roffler, S. R., Cheng, T. L. "Development of a universal anti-polyethylene glycol reporter gene for noninvasive imaging of PEGylated probes” J. Nucl. Med. 2010, 51, 933-941.

(54) Chuang, K. H., Wang, H. E., Chen, F. M., Tzou, S. C., Cheng, C. M., Chang, Y. C., Tseng, W. L., Shiea, J., Lin, S. R., Wang, J. Y., Chen, B. M., Roffler, S. R., Cheng, T. L. ”Endocytosis of PEGylated agents enhances cancer imaging and anticancer efficacy” Mol. Cancer Ther. 2010, 9, 1903-1912

2009   corresponding author

(53) Lin, Y.-H. and and Tseng, W.-L.* “Highly sensitive and selective detection of silver ions and silver nanoparticles in aqueous solution using an oligonucleotide-based fluorogenic probe" Chem. Comm. 2009, 6619–6621

(52) Shen, C.-C. and Tseng, W.-L.* “A One-Step Synthesis of White-light-emitting Quantum Dots at Low Temperature ” Inorg. Chem. 2009, 48, 8689-8694.

(51) Chen, Y.-M., Cheng, T.-L. and Tseng, W.-L.* “Fluorescence Turn-On Detection of Iodide, Iodate and Total Iodine Using Fluorescein-5-Isothiocyanate-Modified Gold Nanoparticles” Analyst 2009, 134, 2106 – 2112.

(50) Li, M.-D., Tseng, W.-L.* and Cheng, T.-L. “Ultrasensitive detection of indoleamines by combination of nanoparticle-based extraction with capillary electrophoresis/laser-induced native fluorescence” J. Chromatogr. A 2009, 1216, 6451-6458.

(49) Yu, C.-J., Cheng, T.-L., and Tseng, W.-L.* “Effects of Mn2+ on Oligonucleotide-Gold Nanoparticle Hybrids for Colorimetric Sensing of Hg2+: Improving Colorimetric Sensitivity and Accelerating Color Change” Biosens. Bioelectron. 2009, 25, 204-210.

(48) Liu, F.-C., Chen, Y.-M., Lin, J.-H. and Tseng, W.-L.* “Synthesis of highly fluorescent glutathione-capped ZnxHg1-xSe quantum dot and its application for sensing copper ion” Journal of Colloid and Interface Science 2009, 337, 414-419.

(47) Huang, C.-C. and Tseng, W.-L.* “Highly Selective Detection of Histidine Using o-Phthaldialdehyde Derivatization After the Removal of Aminothiols Through Tween 20-capped Gold Nanoparticles” Analyst 2009, 134, 1699-1705.

(46) Wu, H.-P., Yu, C-J., Lin, C.-Y., Lin, Y.-H. and Tseng, W.-L.* “Gold nanoparticles as assisted matrices for the detection of biomolecules in a high-salt solution through laser desorption/ionization mass spectrometry” J. Am. Soc. Mass Spectrom. 2009, 20, 875-882.

(45) Li, M.-D. Cheng, T.-L. and Tseng, W.-L.* “Nonionic Surfactant-Capped Gold Nanoparticles for Selective Enrichment of Aminothiols Prior to Capillary Electrophoresis with UV Absorption Detection” Electrophoresis 2009, 1, 388-395.

(44) Lin, C.-Y. and Tseng, W.-L.* “Selective Enrichment of Albumin in biological samples by Capillary Electrophoresis Using Segmental Filling with Sodium Octyl Sulfate in the Background Electrolyte” Electrophoresis 2009, 30, 1-8.

(43) Shen, C.-C., Tseng, W.-L.* and Hsieh, M.-M. “Selective enrichment of aminothiols using Tween 20-capped gold nanoparticles followed by capillary electrophoresis with laser-induced fluorescence” J. Chromatogr. A 2009, 1216, 288-293.

2009   Non-corresponding author

(42) Tseng, W.-L., Hsu, C.-Y., Wu, T.-H., Haung, S.-W., Hsieh, M.-M.* “Highly sensitive detection of chiral amino acids by capillary electrophoresis based on on-line stacking techniques” Electrophoresis 2009, 30, 2558-2564 (first author).

(41) Tzou, S.-C., Roffler, S., Chuang, K.-H., Yeh, H.-P., Kao, C.-H., Su, Y.-C., Cheng, C.-M., Tseng, W. L., Shiea, J., Cheng, K.-W., Tian-Lu Cheng, T.-L.* and Wang, H.-E. “Micro-PET imaging of -glucuronidase activity by the hydrophobic conversion of a glucuronide probe” Radiology, 2009, 252, 754-62

(40) Cheng, C.-M., Chu, P.-Y. Chuang, K.-H., Roffler, S. R. Kao, C.-H., Tseng, W.-L., Shiea, J., Chang, W.-D., Su, Y.-C., Chen, B.-M. Wang, Y.-M. and Cheng, T.-L.* “Hapten-derivatized nanoparticle targeting and imaging of gene expression by multimodality imaging systems” Cancer gene therapy. 2009, 16, 83-90.

2008   Corresponding author

(39) Yu, C.-J. andTseng, W.-L.* “Colorimetric detection of mercury (II) in a high-salinity solution using gold nanoparticles capped with 3-mercaptopropionate acid and adenosine monophosphate” Langmuir 2008, 24, 12717-12722.

(38) Huang, C.-C. and Tseng, W.-L.* “Role of Fluorosurfactant-Modified Gold Nanoparticles in Selective Detection of Homcysteine Thiolactone: Remover and Sensor” Anal. Chem. 2008, 80, 6345-6350.

(37) Lin, C.-Y., Chang, H.-C., and Tseng, W.-L.* “Enrichment and separation of acidic and basic proteins using centrifugal ultrafiltration followed by polyelectrolyte-filled capillary electrophoresis” Electrophoresis 2008, 29, 3024-3031.

(36) Wu, H.-P., Huang, C.-C., Cheng, T.-L. and Tseng, W.-L.* ” Sodium hydroxide as pretreatment and fluorosurfactant-capped gold nanoparticles as sensor for the highly selective detection of cysteine” Talanta 2008, 76, 347-352.

(35) Chen, Y.-M., Yu, C.-J., Cheng, T.-L., and Tseng, W.-L.* “Colorimetric Detection of Lysozyme based on Electrostatic Interaction with Human Serum Albumin-Modified Gold Nanoparticles” Langmuir 2008, 24, 3654-3660. (corresponding author)

(34) Liu, F.-C., Cheng, T.-L., Shen, C.-C., Tseng, W.-L.* , and Chiang, M. Y.* “Synthesis of Cysteine-Capped ZnxCd1-xSe Alloyed Quantum Dots Emitting in the Blue-Green Spectral Range” Langmuir 2008, 24, 2162-2167.

(33) Yu, C.-J., Chang, H.-C., and Tseng, W.-L.* “On-Line Concentration of Proteins by Sodium Dodecyl Sulfate-Capillary Gel Electrophoresis with Laser-Induced Native Fluorescence” Electrophoresis 2008, 29, 483-490.

2008   Non-Corresponding author

(32) Tseng, W.-L., Chen, S.-M., Hsu, C.-Y. and Hsieh, M.-M.* “On-line concentration and separation of indolamines, catecholamines, and metanephrines in capillary electrophoresis using high concentration of poly(diallyldimethylammonium chloride)” Anal. Chim. Acta 2008, 613, 108-115.

(31) Shiea, J., Yuan, C. H., Huang, M. Z., Cheng, S. C., Ma, Y. L., Tseng, W. L., Chang, H. C., Huang, W. C. “Detection of native proteins ions in aqueous solution under ambient condition by electrospray laser desorption/ionization mass spectrometry” Anal. Chem. 2008, 80, 4845-4852.

2007   Corresponding author

(30) Hu, C.-C., Lin, J.-C., Tseng, W.-L.*, Huang, M. F., Chiu, T.-C. and Chang, H.-T.* “Analysis of Dynamic and Thermodynamic Adsorption of Nanoparticles on Solid Surfaces by Dark-field Light Scattering Measurements” J. Chin. Chem. Soc. 2007, 54, 869-878.

(29) Lin, C.-Y., Yu, C.-J., Chen, Y.-M., Chang, H.-C. and Tseng, W.-L.* “Simultaneous separation of anionic and cationic proteins by capillary electrophoresis using high concentration of poly(diallydimethylammonium chloride) as an additive” J. Chromatogr. A 2007, 1165, 219-225.

(28) Wu, H.-P., Su, C.-L., Hui-Chiu Chang and Tseng, W.-L.* “Sample-First Preparation: A Method for Surface-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry Analysis of Cyclic Oligosaccharides” Anal. Chem. 2007, 79, 1626-1633.

(27) Wu, H.-P., Cheng, T.-L, Tseng, W.-L.* “Phosphate-Modified TiO2 Nanoparticles for Selective Detection of Dopamine, Levodopa, Adrenaline, and Catechol Based on Fluorescence Quenching” Langmuir 2007, 23, 7880-7885.

(26) Su, C. -L andTseng, W.-L.* “Gold nanoparticles as Assisted Matrix for Determining Neutral Small Carbohydrates through Laser Desorption/Ionization Time-of-Flight Mass Spectrometry” Anal. Chem. 2007, 79, 1626-1633.

2007   Non-Corresponding author

(25) Lee, K.-H., Huang, K.-M., Tseng, W.-L.*, Chiu, T.-C., Lin, Y.-W. and Chang, H.-T.* “Manipulation of the Growth of Gold and Silver Nanomaterials on Glass by Seeding Approach” Langmuir 2007, 23, 1435-1442.

2006    Corresponding author

(24) Su, C. -L and Tseng, W.-L.* “Selective Detection of Homocysteine under Alkaline Conditions” Rapid Commun. Mass Spectrom. 2006, 20, 3303-3308.

(23) Yu, C. -J. Su, C. -L and Tseng, W.-L.* “Separation of Acidic and Basic Proteins by Nanoparticle-Filled Capillary Electrophoresis” Anal. Chem. 2006, 78, 8004-8010.

(22) Yu, C. –J. and Tseng, W.-L.* “Online concentration and separation of basic proteins using cationic polyelectrolyte in the presence of reversed electroosmotic flow” Electrophoresis 2006, 27, 3569-3577.

(21) Lin, Y. -W., Tseng, W.-L.* and Chang, H. -T.* “Using a Layer-by-Layer Assembly Technique to Fabricate Multiply Colored Films of CdSe@CdS and CdTe Quantum Dots” Adv. Mater. 2006, 18, 1381-1386.

2006    Non-Corresponding author

(20) Hsieh, M. -M., Chiu, T. -C., Tseng, W. -L. and Chang, H. -T.* “Electrophoretic analysis of biomolecules in microchannels using polymer solutions” Current Anal. Chem. 2006, 2, 17-33.

(19) Huang, Y. -F., Hsieh, M. -M., Tseng, W. -L., and Chang, H. -T.* “On-line concentration of microheterogeneous proteins by capillary electrophoresis using SDS and PEO as additives” J. Proteome Res. 2006, 5, 429-436.

2005 (After Ph. D)

(18) Tseng, W. -L., Lee, K. -H. and Chang, H. -T. “Using Nile Red-adsorbed gold nanoparticles to locate glutathione within erythrocytes ” Lamgunir. 2005, 21, 10676-10683.

(19) Tseng, W. -L., Huang, M. -F., Huang, Y. -F. and Chang, H. -T. “Nanoparticle-filled capillary electrophoresis for the separation of long DNA molecules in the presence of hydrodynamic and electrokinetic forces” Electrophoresis 2005, 26, 3069-3075.

(18) Sreedhar, M., Lin, Y. -W., Tseng, W. -L. and Chang, H. -T. “Determination of amplified amines based on pH junction in capillary-electrophoresis with electrochemiluminescence detection” Electrophoresis 2005, 26, 2984-2990.

(17) Yang, Z., Lin, Y. -W., Tseng, W. -L., and Chang, H. -T. “Impacts that pH and metal ion concentration have on the synthesis of bimetallic and trimetallic nanorods from gold seeds” J. Materials Chemistry 2005, 15, 1-6.

(16) Chang, S. Y., Tseng, W. -L., Sreedhar, M. and Chang, H. -T. “Determination of small phosphorous-containing compounds by capillary electrophoresis” Talanta 2005, 66, 411-421.

2002 (Ph. D)

(15) Wang, S. -J., Tseng, W. -L., Lin, Y. -W.and Chang, H. -T. “On-line Concentration of Trace Proteins by pH Junctions in Capillary Electrophoresis with UV absorption Detection” J. Chromatogr. A 2002, 979, 261-270.

(14) Tseng, W. -L., Lin, Y. -W. and Chang, H. -T. “Improved Separation of Microheterogeneities and Isoforms of Proteins by Capillary Electrophoresis Using Segmental Filling with SDS and PEO in Background Electrolyte” Anal. Chem. 2002, 74, 4828-4834.

(13) Tseng, W. -L., Lin, Y. -W., Chen, K. -C. and Chang, H. -T. “Electrophoretic Separations of DNA in Bubble-Shape Microchannels” Electrophoresis 2002, 23, 2477-2484.

(12) Hsieh, M. -M., Hsu, C. -E., Tseng, W. -L. and Chang, H. -T. “Amplification of Small Analytes in Polymer Solution by Capillary Electrophoresis” Electrophoresis 2002, 23, 1633-1641.

(11) Tseng, W. -L., Chang, H. -T., Hsu, S. -M., Chen, R. -J. and Lin, S. “Immunoaffinity Capillary Electrophoresis:Determination of Affinity and Stoichiometry For Antibody-antigen Interaction Kinetics” Electrophoresis 2002, 23, 836-846.

2001 (Ph. D)

(10) Tseng, W. -L., Chiu, T. -C., Weng, J. -M. and Chang, H. -T. “Analysis of Albumins Using Albumin Blue 580 by Capillary Electrophoresis and Laser-Induced Fluorescence” J. Liq. Chromatogr. & Rel. Technol. 2001, 24, 2971-2982.

(9) Tseng, W. -L., Hsieh, M. -M., Wang, S. -J., Huang, C. -C., Lin, Y. -C., Chang, P. -L. and Chang, H. -T. “Analysis of Large-Volume DNA markers and PCR Products by Capillary Electrophoresis in the Presence of Electroosmotic Flow” J. Chromatogr. A 2001, 927, 179-190.

(8) Tseng, W. -L. and Chang, H. -T. “Regulation of Electroosmotic Flow and Electrophoretic Mobility of Proteins for Concentration Without Desalting” J. Chromatogr. A 2001, 924, 93-101.

(7) Huang, M. -F., Hsu, C. -E., Tseng, W. -L., Lin, Y. -C., and Chang, H. -T. “Separation of dsDNA in the Presence of Electroosmotic Flow under discontinuous conditions” Electrophoresis 2001, 22, 2281-2290.

(6) Tseng, W. -L. and Chang, H. -T. “A New Strategy for Optimizing Sensitivity, Speed, and Resolution in Capillary Electrophoretic Separation of DNA” Electrophoresis 2001, 22, 763-770.

2000 (Ph. D)

(5) Tseng, W. -L., Hsieh, M. -M., Wang, S. -J. and Chang, H. -T. “Effect of Ionic Strength, pH, and Polymer Concentration on the Separations of DNA Fragments in the Presence of Electroosmotic Flow” J. Chromatogr. A 2000, 894, 219-230.

(4) Tseng, W. -L. and Chang, H. -T. “On-line Concentration and Separation of Proteins by Capillary Electrophoresis Using Polymer Solutions” Anal. Chem. 2000, 72, 4805-4811.

(3) Hsieh, M. -M., Tseng, W. -L. and Chang, H. -T. “On-Column Preconcentration and Separation of DNA Fragments Using Polymer Solutions in the Presence of Electroosmotic Flow” Electrophoresis 2000, 21, 2904-2910.

(2) Chang, H. -T., Chen, H. -S., Hsieh, M. -M. and Tseng, W. -L. “Electrophoretic Separation of DNA in the Presence of Electroosmotic Flow” Reviews in Anal. Chem. 2000, XIX, 45-74.

(1) Tseng, W.-L., Chiu, T.-C., Weng, J.-M. and Chang, H. -T. “Analysis of albumins using albumin blue 580 by capillary electrophoresis and laser-induced fluorescence” J. Liq. Chrom. & Rel. Technol. 2001, 24, 2971–2982.


Book Chapter

(3) Jia-Hui Lin and Wei-Lung Tseng Chapter 7: Fluorescence Detection of Polyadenylation Reaction Through the Coordination of Adensoine2-Coralyne-Adensoine2” invited chapter, edited by Joanna Rorbach and Agnieszka J. Bobrowicz (Polyadenylation: Methods and Protocols, Methods in Molecular Biology, vol. 1125, Human press, ISBN: )

(2) Yen-Hsiu Lin and Wei-Lung Tseng*Chapter 12: A Sample Preparation Method for Gold Nanoparticle-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry” invited chapter, edited by Toms, Steven A. and Weil, Robert J. (Nanoproteomics, Human press, ISBN 978-61779-318-9, 2011)

(1) Yen-Hsiu Lin and Wei-Lung Tseng* "Chpater 12: Mass spectrometric bioanalysis assisted by noble metal nanoparticles" invited chapter, edited by Chau Lai-Kwan and Huan-Tsung Chang (From Bioimaging to Biosensors: Noble Metal Nanoparticles in Biodetection, ISBN 978-981-4267-24-3)


Conference Paper

(11) Tzu-Heng Chen, Chih-Chun Nieh, and Wei-Lung Tseng “Hydroxyl radical-induced etching of glutathione capped gold nanoparticles to oligomeric Au(I) thiolate complex. 6th International Conference on Nanotechnology: Fundamentals and Applications, Barcelona, Spain

(10) Jhih-Yn Jiang, Tzu-Heng Chen, Yen-Hsiu Lin, and Wei-Lung Tseng “Lysozyme-Directed Synthesis of Platinum Nanoclusters as a Mimic Oxidase for Sensing of Glutathione”. 12th Asian Conference on Analytical Sciences (ASIANALYSIS XII) Aug. 22-24 2013, Fukuoka, Japan

(9) Cheng-Ju Yu and Wei-Lung Tseng*A Gold Nanoparticle-based DNA Sensor for Ultrasensitive Detection of Hg2+ and K+ ions by laser-induced Rayleight Light Scattering” 05/16-19, 2013, ISMM 2013, Xiamen, China

(8) Jia-Hui Lin and Wei-Lung Tseng*Design of a Two- and Three-input DNA Logic Gates Using Oligonucleotides Containing Fluorophore-Quencher Pairs” 05/16-19, 2013, ISMM 2013, Xiamen, China.

(7) Chia-Yin Kuo. and Wei-Lung Tseng*Adenosine-Based Molecular Beacons as Light-Up Probes for Sensing of Heparin in Serum” 05/16-19, 2013, ISMM 2013, Xiamen, China.

(6) H. C. Lee, T. H. Chen, W. L. Tseng and C. H. Lin*, 7th IEEE-NEMS Conference, 2012, pp. 665–658

(5) Tseng W.-L. “Human serum albumin-modified gold nanoparticles for selective enrichment of high-pI proteins followed by capillary electrophoresis with ultraviolet detection” 02/12-15, 2012, MSB 2012, Geneva, Switzerland.

(4) J.-H. Lin and Tseng W.-L.* “Colorimetric Assay for S-adenosylhomocysteine hydrolase activity and inhibition using fluorosurfactant-capped gold nanoparticles” 05/22-26, 2011, IUPAC 2011, Kyoto, Japan.

(3) Liu, C-Y. and Tseng W.-L.* “Colorimetric Assay for Cyanide and Cyanogenic Glycoside Using Polysorbate 40-Stabilized Gold Nanoparticles” 05/22-26, 2011, IUPAC 2011, Kyoto, Japan.

(2) Lin, Y.-H. and Tseng W.-L.* “Ultrasensitive Sensing of Hg(II) and CH3Hg(I) Based on Fluorescence Quenching of Lysozyme-Modified Gold Nanoparticles” 05/28-30, 2010, ISMM 2010, the Hong Kong University of Science and Technology, Hong Kong.

(1) Lin, C.-Y. and Tseng. W.-L.* “Selective Enrichment of Albumin in biological samples by Capillary Electrophoresis Using Segmental Filling with Sodium Octyl Sulfate in the Background Electrolyte” 08/16-20, 2008, HUPO 2008 7th World Congress, Amsterdam, NL.



中文著作

(3) 林佳慧 余政儒 曾韋龍金奈米材料之特殊光學特性應用於感測胺基酸硫醇化學 2013, 71, 159-166.

(2) 林彥琇 余政儒 曾韋龍金奈米材料於感測器之應用化學 2010, 68, 33-45

(1) 余政儒 蘇芷玲 曾韋龍 毛細管之微量蛋白質分析化學2006, 64, 451-458.



校外學術與行政服務

2017-2019                中國化學會「化學」總編輯

2014-2017                化學研究推動中心分析化學小組學術委員

2013                           中國化學會高雄分會理事

2013-2015                中國化學會「化學」編輯委員會

2012                          Dataset Papers in Science: Nanotechnology, Review Editorial Board

2013-2015                Frontiers in Analytical Chemistry, Review Editorial Board

2013-2015                American Journal of Chromatography, Review Editorial board

2012                          協辦第 十八屆分析技術交流研討會

2008                          協辦台 北國際分析化學會議 (ICCT)


校內學術與行政服務

104-106                    轉譯科技醫學研究中心轉譯醫學研究小組組長

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105-106                    跨領域級數據科學研究中心生醫與新創檢測組組長

96-98                        中山大學 研究發展處 業務組組長