Home ／About／Faculty／Professor／Dr. Yu-Ya Lin

Dr. Yu-Ya Lin
Dr. Yu-Ya Lin Assistant Professor
Research Areas Organic synthesis, bioorganic chemistry and its applications, olefin metathesis
highest education Ph. D., University of Oxford, UK
Research room C3020
laboratory
phone (07)5252000 分機3911
E-mail yylin@mail.nsysu.edu.tw
web https://yyllab.wixsite.com/home
 Personal profile

Prof. Lin was educated for most of her life in the UK. She has wide variety of interests from different areas. Inspired by her high school chemistry teacher, she decided to specialize in chemistry. She completed both her MChem degree and DPhil in Organic Chemistry in at the Chemistry Department at University of Oxford under the supervision of Prof. Ben Davis. During her DPhil studies, she worked on developing olefin metathesis for the selective chemical modification on proteins. In 2014, she took up a position as assistant professor at the Chemistry Department of National Sun Yat-sen University. Her research interests include developing new peptide ligation methods and applying these methods in the synthesis of biologically active peptides as well as synthesizing novel functional nanoparticles and polymers.


學歷Education

DPhil in Organic Chemistry, Chemistry Department, University of Oxford (2009-2013)

MChem (First Class Honours), Chemistry Department, University of Oxford (2004-2008)

經歷Experience

Assistant Professor, Department of Chemistry, National Sun Yat-sen University (2014-present)

Teaching Excellence Award, College of Science, NSYSU (2017)

NSYSU Award for Excellent Mentor (2015)

JSPS Postdoctoral Fellowship (short-term) for Foreign Researchers (2011)

EPSRC Doctoral Training Award (2009)

Development of Organic Synthetic Strategy, Peptide Synthesis, Synthesis of biologically-active compounds, Development and Synthesis of novel functional materials.

    著作Works
  1. Jiang, S.-Y.; Hsieh, W.-T.; Chen, W.-S.; Liao, J.-S.; Chiang, P.-Y.; Lin, Y. A.*, Synthesis of Thiol‐Containing Oligopeptides via Tandem Activation of γ‐Thiolactones by Silver‐DABCO Pair. Asian J. Org. Chem. 2020, 9, 1638-1649.
  2. Bhushan, B.; Lin, Y. A.; Bak, M.; Phanumartwiwath, A.; Yang, N.; Bilyard, M. K.; Tanaka, T.; Hudson, K. L.; Lercher, L.; Stegmann, M.; Mohammed, S.; Davis, B. G.*, Genetic Incorporation of Olefin Cross-Metathesis Reaction Tags for Protein Modification. J. Am. Chem. Soc. 2018, 140, 14599-14603.
  3. Huang, K.-J.; Huang, Y.-C.; Lin, Y. A.*, Synthesis of Histidine-Containing Oligopeptides via Histidine-Promoted Peptide Ligation. Chem. Asian J. 2018, 13, 400-403.
  4. Lin, Y. A.; Davis, B. G.*, Vignette: Extending the Application of Metathesis in Chemical Biology – The Development of Site-Selective Peptide and Protein Modifications. Handbook of Metathesis (ISBN: 9783527334247). Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA. Mar, 2015: 295-309.
  5. Lin, Y. A.; Boutureira, O.; Lercher, L.; Bhushan, B.; Paton, R. S.; Davis, B. G.*, Rapid Cross Metathesis for Reversible Protein Modifications via Chemical Access to Se-Allyl Selenocysteine in Proteins. J. Am. Chem. Soc. 2013, 135, 12156-12159.
  6. Lin, Y. A.; Davis, B. G.*, The Allylic Chalcogen Effect in Olefin Metathesis. Beilstein J. Org. Chem. 2010, 6, 1219-1228.
  7. Lin, Y. A.; Chalker, J. M.; Davis, B. G.*, Olefin Cross-Metathesis on Proteins: Investigation of Allylic Chalcogen Effects and Guiding Principles in Metathesis Partner Selection. J. Am. Chem. Soc. 2010, 132, 16805-16811.
  8. Lin, Y. A.; Chalker, J. M.; Davis, B. G.*, Olefin Metathesis for Site-Selective Protein Modification. ChemBioChem 2009, 10, 959-969.
  9. Chalker, J. M.; Bernardes, G. J. L.; Lin, Y. A.; Davis, B. G.*, Chemical Modification of Proteins at Cysteine: Opportunities in Chemistry and Biology. Chem. Asian J. 2009, 4, 630-640.
  10. Chalker, J. M.; Lin, Y. A.; Boutureira, O.; Davis, B. G.*, Enabling olefin metathesis on proteins: chemical methods for installation of S-allyl cysteine. Chem. Commun. 2009, 3714-3716.
  11. Lin, Y. A.; Chalker, J. M.; Floyd, N.; Bernardes, G. J. L.; Davis, B. G.*, Allyl Sulfides Are Privileged Substrates in Aqueous Cross-Metathesis: Application to Site-Selective Protein Modification. J. Am. Chem. Soc. 2008, 130, 9642-9643.
    專利Patents