Home ／About／Faculty／Professor／Dr. Chia C. Wang

Dr. Chia C. Wang
Dr. Chia C. Wang Professor
Research Areas Aerosol science, Biomedical nanoparticles, Aerosol instrumentation
highest education Ph. D., University of California, Berkeley, USA
Research room SC3007
laboratory SC3007
phone (07)5252000 分機3941
E-mail chiawang@mail.nsysu.edu.tw
web https://aerosol.nsysu.edu.tw/staffs-info.asp?id=253
 Personal profile
Dr. Chia C. Wang joined the faculties of Dept. of Chemistry of NSYSU in 2010. Concerning the increasingly severe air pollution globally and particularly in Asia, Dr. Wang began her studies on Earth-related aerosols. Dr. Wang has developed the high resolution aerosol VUV photoelectron spectroscopy and applied it to study the valence electronic structures, interfacial solvation properties, surface pH of aerosols. Her research efforts include: (1) developing novel aerosol characterization techniques and instrument to advance the fundamental physicochemical properties of aerosols, (2) aerosols and their impacts to the atmospheric and marine chemistry and environmental ecosystem, (3) health effects of aerosols and biomedical implications of aerosol therapy, and (4) formation, regulation and removal of anthropogenic aerosols. Dr. Wang’s research also involves the studies of structure-function correlation of hemoglobin and hemoglobin-disorder induced hemoglobinopathies, from which she has developed new therapeutic strategies to treat Hb oxygen-transport defect and hypoxia related diseases, including chronic obstructive pulmonary diseases (COPD). Considering the tremendous impacts of air pollution and PM2.5 (particulate matters ≤ 2.5μm) to the atmosphere, air quality, environmental ecosystem and human health, Dr. Wang has taken the leading role in establishing the Aerosol Science Research Center (ASRC) of NSYSU, which was launched in May 2016 and is currently the first and only aerosol and PM2.5-themed research center in Asia. ASRC actively engages in promoting aerosol research in Taiwan and other countries in Asia, providing a platform to bring researchers from chemistry, physics, environmental engineering, public health, and biological sciences to collectively address the multi-faceted PM2.5-related issues. Dr. Wang also dedicates in the educational outreach activities to promote aerosol science and raise the awareness of environmental protection. She has curated an aerosolthemed science exhibit in 2018, held series of workshops for training seed primary and secondary school teachers for developing novel teaching materials for aerosol sciences, and in 2018, Dr. Wang established the first multi-disciplinary aerosol science program in Asia in 2018 to educate the young generations at the bachelor degree level.

學歷Education

2007 Ph. D. Physical Chemistry, University of California, Berkeley, CA, USA (Advisor: Prof. Daniel M. Neumark)

2001 M.S. Physical Chemistry, National Taiwan University, Taipei, Taiwan, R.O.C. (Advisor: Prof. Yuan T. Lee)

經歷Experience

2016 – Present Founding Director, Aerosol Science Research Center, NSYSU, Kaohsiung, Taiwan, R.O.C.

2017–Present Associate Professor, Department of Chemistry, NSYSU, Kaohsiung, Taiwan, R.O.C.

2016–2017 Director, Division of Industry and Academic Collaboration, Office of Industrial

Collaboration and Continuing Education Affairs, NSYSU, Kaohsiung, Taiwan, R.O.C.

2010 – 2017 Assistant Professor, Department of Chemistry, NSYSU, Kaohsiung, Taiwan, R.O.C.

2008 – 2010 Postdoctoral Fellow, University of British Columbia, Vancouver, B.C. Canada

2008 – 2008 Postdoctoral Fellow, Lawrence Berkeley National Laboratory, Berkeley, CA, USA

• 國立中山大學109學年度團隊績優教師

• 國立中山大學108學年度團隊績優教師

• 國立中山大學105學年度教學領航教師

• 國立中山大學103學年度全校優良導師

• 國立中山大學102學年度全校教學績優教師

• 國立中山大學102學年度理學院傑出教學教師代表

• 國立中山大學102學年度化學系傑出教學績優教師

• 國立中山大學100-102學年度特聘年輕學者

• 國科會100-102年度補助大專校院獎勵特殊優秀人才

I. Aerosol Science

■ Physical chemistry of aerosols: VUV photoelectron spectroscopy of aerosols, vibrational spectroscopy of aerosols, time-resolved kinetic and dynamic properties of aerosols, influences of aerosols to the atmospheric, oceanic and environmental ecosystem

■ Reduction, regulation and removal of PM2.5 pollution sources

■ Biomedical study on anthropogenic aerosols (e.g. PM2.5) associated diseases: including COPD, neurodegenerative diseases, cardiovascular diseases, cancers

■ Development of novel PM2.5 characterization techniques

■ PM2.5 and air quality environmental education

II. Biophysical Chemistry Hemoglobin and hemeproteins: Subunit disassembly/assembly process, Subunit-subunit interaction, Structure-function correlations and association with diseases, Post-translation modifications.

III. Instrumentation developments: Aerosol VUV photoelectron spectroscopy, Long-path, temperature-adjustable aerosol chamber coupled with FTIR.

    著作Works
  1. Prather, K.A.*, Wang, C. C., Schooley, R. T. (2020): Reducing transmission of SARS-CoV-2, Science, 368, 1422-1424.
  2. Bagchi, A., Yu, Y., J.-H., Tsai, C.-C., Hu, W.-P., Wang, C. C.* (2020): Evidence and evolution of Criegee intermediates, hydroperoxides and secondary organic aerosols formed via ozonolysis of α-pinene, Phys. Chem. Chem. Phys., 22, 6528-6537.
  3. Chen, W.-R., Chou, C.-C., Wang, C.C.* (2019): Phthalides serve as potent modulators to boost the efficacy of fetal hemoglobin induction therapy for β-hemoglobinopathies. Blood Adv., 3, 1493-1498.
  4. Lee, F.-Y., Lee, M. S., Wallace, C. G., Huang, C.-R., Chu, C.-H., Weng, Z.-H., Huang, J.-H., Chen, X.-S., Wang, C. C.*, Yip, H.-K.* (2019): Short-interval exposure to ambient fine particulate matter (PM2.5) exacerbates the susceptibility of pulmonary damage in setting of lung ischemia-reperfusion
  5. Wang, C. C.*(2019): VUV aerosol photoelectron spectroscopy and its implications in aerosol and biomedical sciences. Chemistry, 77(2), 165-172. (invited article)
  6. Chen, W.-R., Yu, Y., Zulfajri, M., Lin, P.-C., Wu, Z.-H., Chen, M.-S., Wang, C. C.* (2017): Phthalide derivatives from Angelica sinensis decrease oxygen affinity of hemoglobin: A new allostericmodulating mechanism and potential use as 2,3-BPG substitutes. Sci. Rep. 7, 5504.
  7. Lin, P.-C., Wu, Z.-H., Chen, M.-S., Li, Y.-L., Chen, W.-R., Huang, T.-P., Lee, Y.-Y. and Wang, C. C.* (2017): Interfacial solvation and surface pH of phenol and dihydroxybenzene aqueous nanoaerosols unveiled by aerosol VUV photoelectron spectroscopy. J. Phys. Chem. B 121, 1054-1067.
  8. Chang, P.-C., Yu, Y., Wu, Z.-H., Lin, P.-C., Chen, W.-R., Su, C.-C., Chen, M.-S., Li Y.-L., Huang T.- P., Lee Y.-Y., Wang, C. C.* (2016): Molecular basis of the antioxidant capability of glutathione unraveled via aerosol VUV photoelectron spectroscopy. J. Phys. Chem. B 120, 10181-10191.
  9. Su, C.-C., Yu, Y., Chang, P.-C., Chen, Y.-W., Chen, I-Y., Lee, Y.-Y., Wang, C. C.* (2015): VUV photoelectron spectroscopy of aqueous cysteine aerosols: A microscopic view of its nucleophilicity at varying pH conditions. J. Phys. Chem. Lett. 6, 817-823.
  10. Chen, Y.-C., Hsu, C.-K., Wang, C. C., Tsai, P.-J., Wang, C.-Y., Chen, M.-R., Lin M.-Y., (2015): Particulate matter exposure in a police station located near a highway. Int. J. Environ. Res. Public Health 12, 14541-14556.
  11. Kan, H.-I., Chen, Y.-Y., Wang, C. C.* (2013): Subunit disassembly of human hemoglobin unravels the site-specific roles of its cysteine residues. J. Phys. Chem. B, 117, 9831-9839.
  12. Preston, T. C., Wang, C. C., Signorell, R. (2012): Infrared spectroscopy and modeling of cocrystalline CO2·C2H2 aerosol particles. I. The formation and decomposition of co-crystalline CO2·C2H2 aerosol particles. J. Chem. Phys. 136, 094509.
  13. Chang, K.-C., Tsai, T.-M., Chang, T.-C., Syu, Y.-E., Wang, C. C., Chuang, S.-L., Li, C.-H., Gan, D.- S., Sze, S. M. (2011): Reducing operation current of Ni-doped silicon oxide resistance random access memory by supercritical CO2 fluid treatment. Appl. Phys. Lett. 99, 263501
  14. Lang, E. K., Knox, K. J., Wang, C. C., Signorell, R. (2011): The influence of methane, acetylene and carbon dioxide on the crystallization of supercooled ethane droplets in Titan’s clouds. Planet. Space Sci. 59, 722-732.
  15. Wang, C. C., Lang, E. K., Signorell, R. (2010): Methane gas stabilizes supercooled ethane droplets in Titan’s clouds. Astrophysical J. 712, L40-L43.
  16. Wang, C. C., Atreya, S. M., Signorell, R. (2010): Evidence of layered methane clouds in Titan’s atmosphere. Icarus, 206, 787-790.
  17. Kornilov, O., Wang, C. C., Healy, A. T., Leonard, M., Peng, C., Leone, S. R., Neumark, D. M., Gessner, O. (2010): Ultrafast dynamics in Helium nanodroplets probed by femtosecond time-resolved EUV photoelectron imaging. J. Phys. Chem. A 114, 1437-1445.
  18. Wang, C. C., Zielke, P., Sigurbjörnsson, Ó. F., Viteri, R., Signorell, R. (2009): Infrared Spectra of C2H6, C2H4, C2H2 and CO2 aerosols potentially formed in Titan’s Atmosphere. J. Phys. Chem. A 113, 11129-11137.
  19. Wang, C. C., Kornilov, O., Kim, J. H., Peterka, D. S., Gessner, O., Neumark, D. M. (2008): Photoelectron imaging of Helium droplets doped with Kr and Xe atoms. J. Phys. Chem. A 112, 9356-9365.
  20. Peterka, D. S., Kim, J. H., Wang, C. C., Poisson, L., Neumark, D. M. (2007): Photoionization dynamics in pure Helium droplets. J. Phys. Chem. A 111, 7449-7459.
  21. Peterka, D. S., Kim, J. H., Wang, C. C., Neumark, D. M. (2006): Photoionization and photofragmentation of SF6 in Helium nanodroplets. J. Phys. Chem. B 110, 19945-19955.
  22. Kim, J. H., Peterka, D. S., Wang, C. C., Neumark, D. M. (2006): Photoionization of Helium nanodroplets doped with rare gas atoms. J. Chem. Phys. 124, 214301.
  23. Zhang, J., Dai, D., Wang, C. C., Harich, S. A., Wang, X., Yang, X., Gustafsson, M., Skodje, R. T. (2006): State-to-state dynamics of D ＋ H2  HD ＋ H control of transition state pathway via reagent orientation. Phys. Rev. Lett., 96, 093201.
  24. Dai, D., Wang, C. C., Wu, G., Harich, S. A., Song, H., Hayes, M., Skodje, R. T., Wang, X., Gerlich, D. and Yang, X. (2005): State-to-state dynamics of high-n Rydberg H-atom scattering with D2. Phys. Rev. Lett. 95, 013201.
  25. Song, H., Dai, D., Wu, G., Wang, C. C., Harich, S. A., Hayes, M. Y., Wang, X., Gerlich, D., Yang, X., Skodje, R. T. (2005): Chemical reaction dynamics of Rydberg atoms with neutral molecules: a comparison of molecular-beam and classical trajectory results for the H(n) ＋ D2 HD ＋D (n’). J. Chem. Phys. 123, 074314.
  26. Dai, D., Wang, C. C., Harich, S. A., Wang, X., Yang, X., Chao, S. D., Skodje, R. T. (2003): Interference of quantized transition-state pathways in the H ＋ D2  D ＋ HD chemical reaction. Science 300, 1730-1734.
  27. Schroden, J. J., Wang, C. C., Davis, H.F. (2003): Competition between C-C versus C-H activation in reactions of neutral Yttrium atoms with four butene isomers. J. Phys. Chem. A 107, 9295-9300.
  28. Harich, S. A., Dai, D., Wang, C. C., Yang, X., Chao, S. D., Skodje, R. T. (2002) : Forward scattering due to slow-down of the intermediate in the H ＋ HD  D ＋ H2 reaction. Nature 419, 281-284.
  29. Wang, C. C., Lee, Y. T., Lin, J. J., Shu, J., Lee, Y.-Y., Yang, X. (2002): Photodissociation dynamics of cyclopropane at 157 nm. J. Chem. Phys. 117, 153-160.
  30. Wang, C. C., Shu, J., Lin, J. J., Lee, Y. T., Yang, X., Nguyen, T. L., Mebel, A. M. (2002): Experimental and theoretical investigation of the O(1D) reaction with cyclopropane. J. Chem. Phys. 116, 8292-8299.
  31. Liu X., Wang, C. C., Lin, J. J., Harich, S. A. and Yang, X. (2002): Effect of a single quantum rotational excitation on state-to-state dynamics of the O(1D) ＋ H2 reaction. Phys. Rev. Lett. 89, 133201
  32. Chao, S. D., Harich, S. A., Dai, D., Wang, C. C., Yang, X., Skodje, R. T. (2002): A full state- and angle-resolved study of the H ＋ HD  D ＋ H2 reaction: comparison of a molecular beam experiment to ab initio quantum reaction dynamics. J. Chem. Phys. 117, 8341-8361.
  33. Aoiz, F. J., Banares, L., Castillo, J. F., Herrero, V. J., Martinez-Haya, B., Honvault, P., Launay, J. M., Liu, X., Lin, J. J., Harich, S. A., Wang, C. C., Yang, X. (2002): The O(1D) ＋ H2 reaction at 56 meV collision energy: a comparison between quantum mechanical, quasiclassical trajectory and crossed beam results. J. Chem. Phys. 116, 10692-10703.
  34. Shu, J., Lin, J. J., Wang, C. C., Lee, Y. T., Yang, X. (2001): Crossed beam studies of the O(1D) ＋ NH3 reaction. J. Chem. Phys. 115, 842-848.
  35. Shu, J., Lin, J. J., Wang, C. C., Lee, Y. T., Yang, X., Nguyen, T. L., Mebel, A. M. (2001): O(1D) reaction with cyclopropane: Evidence of O atom insertion into the C-C bond. J. Chem. Phys. 115, 7-10.
  36. Lin, J. J., Wang, C. C., Lee, Y. T., Yang, X. (2000): Site-specific dissociation dynamics of ethylene at 157 nm: atomic and molecular hydrogen elimination. J. Chem. Phys. 113, 9668-9677.
    專利Patents
  1. Wang, C. C., Chen, W.-R. (2018): Method for enhancing the oxygen level of tissue cells as an alternative method for hyperbaric oxygen therapy. United States of America Patent (Patent No US 9,937,150 B2)
  2. Wang, C. C., Chen, W.-R., (2018): Method for enhancing the oxygen level of tissue cells as an alternative method for hyperbaric oxygen therapy. Republic of China Patent (Patent No TW I643615 B)
  3. Wang, C. C., Chen, W.-R. (2018): Use of phthalides in the preparation of medicinal composition for treating Alzheimer’s disease and 2,3-Biphosphoglycerate metabolism disorder induced morbidities. Republic of China Patent (Patent No TW I638655 B)
  4. Wang, C. C., Zulfajri, M., Yu, Y. (2018): A method for improving the oxygen-releasing ability of hemoglobin to organs and peripheral tissues in human bodies and a medication thereof. United States of America Patent (Patent No US 10,047,063 B2)
  5. Wang, C. C. (2017): An adjustable aerodynamic lenses system for aerodynamic focusing of aerosols. Republic of China Patent (Patent No TW I584344 B)
  6. Wang, C. C., Chen, W.-R. (2017): Method for facilitating the oxygen release of hemoglobin-based blood substitutes. United States of America Patent (Patent No US 9,713,602 B1)
  7. Wang, C. C., Zulfajri, M., Yu, Y. (2017): A method for improving the oxygen-releasing ability of hemoglobin to organs and peripheral tissues in human bodies and its medication mixture. Republic of China Patent (Patent No TW I602564 B)
  8. Wang, C. C., Zulfajri, M., Yu, Y. (2016): A use of ferulic acid for manufacturing drugs for improving the oxygen-releasing ability of hemoglobin to organs and peripheral tissues in human bodies. Republic of China Patent (Patent No TW I532482 B)