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Dr. Po-Ling Chang

Dr. Po-Ling Chang Professor
Research Areas Bioanalytical chemistry, Super-resolution microscopy
highest education Ph. D. National Taiwan University, Taiwan
Research room C2008-2
laboratory
phone (07)5252000 分機3921
E-mail poling@mail.nsysu.edu.tw
web https://tunghaichem.wixsite.com/polingchang
 Personal profile

Dr. Po-Ling Chang got his college diploma from Yanpei Medical Biotechnology College and worked in Division of Blood Bank in the Mackey Memorial Hospital with Prof. Marie Lin and Prof Hisn-Tsung Ho. Afterward, he received his Ph.D. degree from Prof. Huan-Tsung Chang (Department of Chemistry, National Taiwan University) in 2007. Thereafter, he joins to Molecular Medicine Research Center, Chang Gung University (with Prof. Hua-Chien Chen and Prof. Shu-Jen Chen) for postdoctoral training. Since then, he has been on the chemistry faculty at Tunghai University, where he is currently Associate Professor since 2013. In 2015, Dr. Chang spent one year sabbatical in EPFL for nanocapillary and PALM/STORM instrumentation at LBEN (Prof. Aleksandra Radenovic).


學歷Education

2003 -2007 PhD, Department of Chemistry (Analytical), National Taiwan University

2000 -2002 Master, Department of Chemistry (Analytical), National Taiwan University

1993 - 1998 Associate, Department of Medical Technology, Yuanpei Institute of Medical Technology

經歷Experience

2018 - 2020 Chairman of Department of Chemistry, Tunghai University

2018 - Professor of Chemistry

2015 - 2016Visiting professor (Institute of Bioengineering, EPFL, Switzerland)

2013 - 2018 Associate professor (Department of Chemistry, Tunghai University)

2013 - 2015 Director of Precision Instrument Center

2009 - 2013 Assistant professor (Department of Chemistry, Tunghai University)

2007 - 2009 Postdoctoral researcher (Molecular Medicine Research Center, Chang Gung University)

1999 - 2003 Medical technologist (Department of Laboratory Medicine, Mackay Memorial Hospital)

    著作Works
  1. Chang, P.-L.*; Graf, M.; Hung, C.-H.; Radenovic, A., Orthogonal tip-to-tip nanocapillary alignment allows for easy detection of fluorescent emitters in femtomolar concentrations. Nano Lett. 2018, 18 (5), 3165-3171.
  2. Lin, Y.-Z.; Ou, D.-L.; Chang, H.-Y.; Lin, W.-Y.; Hsu, C.; Chang, P.-L.*, Simultaneous visualization of the subfemtomolar expression of microRNA and microRNA target gene using HILO microscopy. Chem. Sci. 2017, 8 (9), 6670-6678.
  3. Chang, P.-L.; Hsieh, M.-M.; Chiu, T.-C., Recent Advances in the Determination of Pesticides in Environmental Samples by Capillary Electrophoresis. Int. J. Env. Res. Public Health 2016, 13 (4), 409.
  4. Chung, Y.-A.; Chen, Y.-H.; Chang, P.-L.*, Strategies of fluorescence staining for trace total ribonucleic acid analysis by capillary electrophoresis with argon ion laser-induced fluorescence. Electrophoresis 2015, 36 (15), 1781-1784.
  5. Chen, Y.-C.; Chang, P.-L.*, Baseline separation of amino acid biomarkers of hepatocellular carcinoma by polyvinylpyrrolidone-filled capillary electrophoresis with light-emitting diode-induced fluorescence in the presence of mixed micelles. Analyst 2015, 140 (3), 847-853.
  6. Yu, M.-H.; Huang, Y.-C.; Chang, P.-L.*, Rapid screening of the heterogeneity of DNA methylation by single-strand conformation polymorphism and CE-LIF in the presence of electro-osmotic flow. Electrophoresis 2014, 35, 2378-2385.
  7. Shih, Y.-C.; Liao, C.-R.; Chung, I.-C.; Chang, Y.-S.; Chang, P.-L.*, Simultaneous separation of five major ribonucleic acids by capillary electrophoresis with laser-induced fluorescence in the presence of electroosmotic flow: Application to the rapid screening of 5S rRNA from ovarian cancer cells. Anal. Chim. Acta 2014, 847, 73-79.
  8. Lin, Y.-Z.; Chang, P.-L.*, Colorimetric Determination of DNA Methylation Based on the Strength of the Hydrophobic Interactions between DNA and Gold Nanoparticles. ACS Appl. Mater. Interfaces 2013, 5 (22), 12045-51.
    專利Patents